Pavel Wohl, Alzbeta Krausova, Petr Wohl, Ondrej Fabian, Lukas Bajer, Jan Brezina, Pavel Drastich, Mojmír Hlavaty, Petra Novotna, Michal Kahle, Julius Spicak, Martin Gregor
{"title":"Limited Validity of Mayo Endoscopic Subscore in Ulcerative Colitis with Concomitant Primary Sclerosing Cholangitis","authors":"Pavel Wohl, Alzbeta Krausova, Petr Wohl, Ondrej Fabian, Lukas Bajer, Jan Brezina, Pavel Drastich, Mojmír Hlavaty, Petra Novotna, Michal Kahle, Julius Spicak, Martin Gregor","doi":"10.1101/2024.04.08.24305005","DOIUrl":null,"url":null,"abstract":"<strong>Background and Aims</strong> Ulcerative colitis (UC) with concomitant primary sclerosing cholangitis (PSC) represents a distinct disease entity (PSC-UC). Mayo endoscopic subscore (MES) is a standard tool for assessing disease activity in UC but its relevance in PSC-UC remains unclear. Here, we sought to compare MES in a cohort of UC and PSC-UC patients and assess the accuracy using histological activity scoring (Nancy histological index; NHI).","PeriodicalId":501258,"journal":{"name":"medRxiv - Gastroenterology","volume":"65 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"medRxiv - Gastroenterology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1101/2024.04.08.24305005","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Background and Aims Ulcerative colitis (UC) with concomitant primary sclerosing cholangitis (PSC) represents a distinct disease entity (PSC-UC). Mayo endoscopic subscore (MES) is a standard tool for assessing disease activity in UC but its relevance in PSC-UC remains unclear. Here, we sought to compare MES in a cohort of UC and PSC-UC patients and assess the accuracy using histological activity scoring (Nancy histological index; NHI).
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