The use of uncemented stems in femoral neck fractures in elderly patients: A comparative study of 671 cases

IF 2.3 3区 医学 Q2 ORTHOPEDICS Orthopaedics & Traumatology-Surgery & Research Pub Date : 2024-06-01 DOI:10.1016/j.otsr.2024.103878
Alexandre Gounot , Anahita Charlot , Pascal Guillon , Augustin Schaefer , Aymane Moslemi , Pierre Boutroux , Alain Sautet
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引用次数: 0

Abstract

Introduction

The use of cemented stems in elderly patients is associated with the risk of intraoperative embolic complications. Uncemented stems eliminate this risk, but their use is controversial because of the risk of mechanical complications, with estimated subsidence between 3.6 and 30% and periprosthetic fractures between 2.1 and 11% at 6 weeks. A retrospective multicenter comparative study was conducted using a propensity score analysis to evaluate mechanical performances of uncemented stems in femoral neck fractures in elderly patients to (1) compare the risk of mechanical complications and (2) assess the use of metaphyseal-anchored stems for this indication.

Hypothesis

There is no difference in the risk of mechanical complications, intraoperatively or postoperatively, between these stems.

Materials and methods

We conducted a multicenter retrospective comparative study including 358 uncemented and 313 cemented stems. The mean age was 84.5 years [83.9–85.1]. The inclusion criteria were patients 70 years and older and a follow-up of at least 6 weeks. The primary endpoint was a composite endpoint comprised of stem subsidence  2 mm or periprosthetic fracture (up to 3 months postoperatively). The secondary endpoints were infection, stem subsidence  2 mm, and operative time. These endpoints were analyzed using a propensity score to control confounding factors. A secondary analysis used the same endpoints to compare metaphyseal-anchored (short stems) versus Corail-like stems.

Results

After adjusting for the propensity score, we found 11.17% mechanical complications in the uncemented group (n = 40, 5.59% subsidence, and 5.59% fractures) versus 13.42% for the cemented group (n = 42, 7.99% subsidence, and 5.43% fractures). There was no statistically significant difference between the 2 values (Odds Ratio [OR] = 0.64 [95% Confidence Interval [CI]: 0.14–2.85] [p = 0.7]). The mortality rate due to cement embolism was 1%. There was no difference in the rate of subsidence (OR = 0.55 [95% CI: 0.02–12.5] [p = 0.7]), periprosthetic fracture (OR = 0.65 [95% CI: 0.13–3.12] [p = 0.7]) or infection (OR = 0.71 [95% CI: 0.32–1.55] [p = 0.4]). However, the operative times were longer in the cemented group (p = 0.03 for hemiarthroplasties [mean additional time 16 minutes] and p = 0.02 for total hip arthroplasties [mean additional time 22 minutes]). No difference was observed between the metaphyseal-anchored (short stems) and Corail-like stems regarding operative time, rate of infection, and rate of stem subsidence or periprosthetic fractures.

Discussion

This is one of the first studies to highlight cemented stem subsidence when used for femoral neck fractures in elderly patients. Using uncemented stems in this indication is still warranted, especially since they do not bring about more mechanical complications in the first few months. Metaphyseal-anchored short stems seem to give the same results as “standard” stems. However, these findings need to be assessed in the longer term.

Level of evidence

III; retrospective comparative study.

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在老年股骨颈骨折中使用非骨水泥柄:671 例病例的对比研究
老年患者使用骨水泥基台与术中栓塞并发症的风险有关。非骨水泥柄可消除这一风险,但由于其机械并发症的风险,其使用仍存在争议,估计6周后的下沉率在3.6%至30%之间,假体周围骨折率在2.1%至11%之间。一项回顾性多中心比较研究采用倾向评分分析法对老年股骨颈骨折患者使用非骨水泥柄的机械性能进行了评估,目的是:(1) 比较机械并发症的风险;(2) 评估骨骺锚定柄在这一适应症中的应用。这些骨干在术中或术后发生机械并发症的风险并无差别。我们进行了一项多中心回顾性比较研究,其中包括 358 例非骨水泥基台和 313 例骨水泥基台。平均年龄为 84.5 岁 [83.9-85.1]。纳入标准为 70 岁及以上患者,随访至少 6 周。主要终点是由柄下沉≥2毫米或假体周围骨折(术后3个月内)组成的复合终点。次要终点是感染、骨干下沉≥2毫米和手术时间。这些终点采用倾向评分进行分析,以控制混杂因素。一项辅助分析使用相同的终点来比较骺板锚定(短茎)和Corail样茎。在对倾向评分进行调整后,我们发现非骨水泥组的机械并发症发生率为11.17%(=40,5.59%下沉,5.59%骨折),而骨水泥组的机械并发症发生率为13.42%(=42,7.99%下沉,5.43%骨折)。这两个数值在统计学上没有明显差异(比值比 [OR]=0.64 [95% 置信区间 [CI]:0.14-2.85] [=0.7])。水泥栓塞导致的死亡率为1%。下沉率(OR=0.55 [95% CI:0.02-12.5] [=0.7])、假体周围骨折率(OR=0.65 [95% CI:0.13-3.12] [=0.7])或感染率(OR=0.71 [95% CI:0.32-1.55] [=0.4])没有差异。不过,骨水泥组的手术时间更长(半髋关节置换=0.03[平均额外时间16分钟],全髋关节置换=0.02[平均额外时间22分钟])。在手术时间、感染率、骨干下沉率或假体周围骨折率方面,骺端锚定(短骨干)骨干与Corail样骨干之间未发现差异。这是首批强调老年患者股骨颈骨折时骨水泥柄下沉的研究之一。在这一适应症中使用非骨水泥柄仍然是有必要的,尤其是在最初的几个月中它们不会带来更多的机械并发症。骺板锚定短柄似乎与 "标准 "柄的效果相同。不过,这些结果还需要长期评估。III;回顾性比较研究。
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来源期刊
CiteScore
5.10
自引率
26.10%
发文量
329
审稿时长
12.5 weeks
期刊介绍: Orthopaedics & Traumatology: Surgery & Research (OTSR) publishes original scientific work in English related to all domains of orthopaedics. Original articles, Reviews, Technical notes and Concise follow-up of a former OTSR study are published in English in electronic form only and indexed in the main international databases.
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