Deoxygenation of N-heterocyclic N-oxides with Selectfluor and disulfane

Abstract

Herein, we describe a metal-free methodology using Selectfluor with disulfane, for the deoxygenation of N-heterocyclic N-oxides (33 examples). This effective, robust, and simple methodology enables the synthesis of various deoxygenated analogues from a wide range of N-heterocyclic N-oxide cores at room temperature in short reaction times with quantitative yields.