Hemophagocytic lymphohistiocytosis in Egyptian children: diagnosis, treatment challenges and outcome

IF 2.3 4区医学 Q2 HEMATOLOGY Expert Review of Hematology Pub Date : 2024-04-10 DOI:10.1080/17474086.2024.2341044

Azza A Tantawy, Nayera H.K. Elsherif, Solaf M Elsayed, Heba G.A. Ali, Sara M Makkeyah, Hisham I.E Elsantiel, Geneviève de Saint Basile, Iman A Ragab

引用次数: 0

Abstract

Hemophagocyticlymphohistiocytosis (HLH) is a spectrum of immune activation which could be genetically determined, or secondaryto an underlying illness. Our aim was to present the clinico-genetic as...

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埃及儿童嗜血细胞淋巴组织细胞增多症：诊断、治疗挑战和结果

嗜血细胞淋巴组织细胞增生症（HLH）是一种免疫激活综合征，可能由基因决定，也可能继发于潜在疾病。我们的目的是介绍嗜血细胞淋巴细胞增多症的临床遗传学特征。

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来源期刊

Expert Review of Hematology HEMATOLOGY-

CiteScore

4.70

自引率

3.60%

发文量

审稿时长

6-12 weeks

期刊介绍： Advanced molecular research techniques have transformed hematology in recent years. With improved understanding of hematologic diseases, we now have the opportunity to research and evaluate new biological therapies, new drugs and drug combinations, new treatment schedules and novel approaches including stem cell transplantation. We can also expect proteomics, molecular genetics and biomarker research to facilitate new diagnostic approaches and the identification of appropriate therapies. Further advances in our knowledge regarding the formation and function of blood cells and blood-forming tissues should ensue, and it will be a major challenge for hematologists to adopt these new paradigms and develop integrated strategies to define the best possible patient care. Expert Review of Hematology (1747-4086) puts these advances in context and explores how they will translate directly into clinical practice.