Katherine M. Winner, Rishi Chanderraj, Ying He, Mark Nuppnau, Robert J. Woods, Michael Heung, Jennifer A. Schaub, Michael W. Sjoding, Robert P. Dickson
{"title":"Preregistered analytic plan: the gut microbiome and acute kidney injury in sepsis","authors":"Katherine M. Winner, Rishi Chanderraj, Ying He, Mark Nuppnau, Robert J. Woods, Michael Heung, Jennifer A. Schaub, Michael W. Sjoding, Robert P. Dickson","doi":"10.1101/2024.04.04.24305205","DOIUrl":null,"url":null,"abstract":"<strong>Overview</strong> We here share a pre-registered analytic plan for a matched case-control study nested in a retrospective cohort of hospitalized patients with suspected sepsis. We will compare gut microbiota (measured near the time of admission) among patients with sepsis who do and do not develop sepsis-induced acute kidney injury.","PeriodicalId":501249,"journal":{"name":"medRxiv - Intensive Care and Critical Care Medicine","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"medRxiv - Intensive Care and Critical Care Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1101/2024.04.04.24305205","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Overview We here share a pre-registered analytic plan for a matched case-control study nested in a retrospective cohort of hospitalized patients with suspected sepsis. We will compare gut microbiota (measured near the time of admission) among patients with sepsis who do and do not develop sepsis-induced acute kidney injury.