Specific Features of the Crystal Structure of Calcium Hydroxyapatite in Native Bone Tissue

IF 0.6 4区 材料科学 Q4 CRYSTALLOGRAPHY Crystallography Reports Pub Date : 2024-04-16 DOI:10.1134/s1063774523601326
A. A. Pavlychev, X. O. Brykalova, A. V. Korneev, A. A. Cherny, N. N. Kornilov
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Abstract

The effects of physiological and pathogenic factors on the crystal structure of calcium hydroxyapatite Ca10(PO4)6(OH)2 in mineralized bone tissues are considered. The unit cell constants of bioapatite, the unit cell deformation, and the crystallite sizes in different groups of bone tissues were analyzed based on the results of X-ray diffraction studies. The main mechanisms responsible for spatial-temporal changes in bone nanostructures were revealed. It was demonstrated that, along with violations of the stoichiometry, an important role is played by the crystallite sizes, estimated as the coherent scattering regions, the number of atoms in which differs by more than two orders of magnitude, and electrostatic interactions between the unbalanced charges of nanocrystallites and hydrated nanolayers of the mineral matrix.

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原生骨组织中羟基磷灰石钙晶体结构的具体特征
摘要 研究了生理和致病因素对矿化骨组织中羟基磷灰石钙 Ca10(PO4)6(OH)2 晶体结构的影响。根据 X 射线衍射研究的结果,分析了不同组骨组织中生物磷灰石的单胞常数、单胞变形和晶粒尺寸。揭示了造成骨纳米结构时空变化的主要机制。结果表明,除了违反化学计量学之外,晶体尺寸也发挥了重要作用,据估计,相干散射区域的原子数相差超过两个数量级,纳米晶体的不平衡电荷与矿物基质的水合纳米层之间存在静电相互作用。
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来源期刊
Crystallography Reports
Crystallography Reports 化学-晶体学
CiteScore
1.10
自引率
28.60%
发文量
96
审稿时长
4-8 weeks
期刊介绍: Crystallography Reports is a journal that publishes original articles short communications, and reviews on various aspects of crystallography: diffraction and scattering of X-rays, electrons, and neutrons, determination of crystal structure of inorganic and organic substances, including proteins and other biological substances; UV-VIS and IR spectroscopy; growth, imperfect structure and physical properties of crystals; thin films, liquid crystals, nanomaterials, partially disordered systems, and the methods of studies.
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