Allogeneic CD19/CD22 CAR T-Cell Therapy for B-Cell Acute Lymphoblastic Leukemia

IF 22.5 1区 医学 Q1 ONCOLOGY JAMA Oncology Pub Date : 2024-04-18 DOI:10.1001/jamaoncol.2024.0473
Laurent Phely, Luca Hensen, Christoph Faul, Christer Alexander Ruff, Dina Schneider, Wolfgang Andreas Bethge, Claudia Lengerke
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Abstract

This case series reports durable remissions in 2 patients with relapsed/refractory B-cell acute lymphoblastic leukemia treated with allogeneic bispecific CD19/CD22-targeting chimeric antigen receptor T cells.
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异体 CD19/CD22 CAR T 细胞疗法治疗 B 细胞急性淋巴细胞白血病
本系列病例报告了两名接受异体双特异性 CD19/CD22 靶向嵌合抗原受体 T 细胞治疗的复发/难治性 B 细胞急性淋巴细胞白血病患者的持久缓解情况。
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来源期刊
JAMA Oncology
JAMA Oncology Medicine-Oncology
自引率
1.80%
发文量
423
期刊介绍: JAMA Oncology is an international peer-reviewed journal that serves as the leading publication for scientists, clinicians, and trainees working in the field of oncology. It is part of the JAMA Network, a collection of peer-reviewed medical and specialty publications.
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