Epicardial Adipose Tissue Thickness and Preserved Ejection Fraction Heart Failure

IF 3.9 2区医学 Q1 PERIPHERAL VASCULAR DISEASE Current Hypertension Reports Pub Date : 2024-04-20 DOI:10.1007/s11906-024-01302-7

Aneesh Dhore-Patil, Daniela Urina-Jassir, Rohan Samson, Thierry H. Le Jemtel, Suzanne Oparil

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Abstract

Purpose of the Review

Preserved ejection fraction heart failure and obesity frequently coexist. Whether obesity plays a consistent role in the pathogenesis of preserved ejection fraction heart failure is unclear. Accumulation of visceral adiposity underlies the pathogenic aftermaths of obesity. However, visceral adiposity imaging is assessed by computed tomography or magnetic resonance and thus not routinely available. In contrast, epicardial adiposity thickness is assessed by echocardiography and thus routinely available. We review the rationale for assessing epicardial adiposity thickness in patients with preserved ejection fraction heart failure and elevated body mass index.

Recent Findings

Body mass index correlates poorly with visceral, and epicardial adiposity. Visceral and epicardial adiposity enlarges as preserved ejection fraction heart failure progresses. Epicardial adiposity may hasten the progression of coronary artery disease and impairs left ventricular sub-endocardial perfusion and diastolic function.

Summary

Epicardial adiposity thickness may help monitor the therapeutic response in patients with preserved ejection failure heart failure and elevated body mass index.

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心外膜脂肪组织厚度与保留射血分数心衰

综述目的射血分数保留型心力衰竭和肥胖经常同时存在。肥胖在射血分数保留型心力衰竭的发病机制中是否起着一致的作用尚不清楚。内脏脂肪堆积是肥胖致病后遗症的基础。然而，内脏脂肪成像是通过计算机断层扫描或磁共振成像进行评估的，因此并不常见。与此相反，心外膜脂肪厚度可通过超声心动图进行评估，因此可常规使用。我们回顾了在射血分数保留、体重指数升高的心力衰竭患者中评估心外膜脂肪厚度的基本原理。内脏和心外膜脂肪随着射血分数保留型心力衰竭的进展而增加。摘要心外膜脂肪厚度有助于监测射血分数保留型心力衰竭患者的治疗反应。

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来源期刊

Current Hypertension Reports 医学-外周血管病

CiteScore

10.50

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： This journal intends to provide clear, insightful, balanced contributions by international experts that review the most important, recently published clinical findings related to the diagnosis, treatment, management, and prevention of hypertension. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas, such as antihypertensive therapies, associated metabolic disorders, and therapeutic trials. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research. Commentaries from well-known figures in the field are also provided.