Advances in nanotechnology for improving the targeted delivery and activity of amphotericin B (2011–2023): a systematic review

IF 3.6 3区 医学 Q3 NANOSCIENCE & NANOTECHNOLOGY Nanotoxicology Pub Date : 2024-04-22 DOI:10.1080/17435390.2024.2340467
Tahereh Zadeh Mehrizi, Nariman Mossafa, Mohammad Vodjgani, Hasan Ebrahimi Shahmabadi
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Abstract

Amphotericin B (AmB) is a broad-spectrum therapeutic and effective drug, but it has serious side effects of toxicity and solubility. Therefore, reducing its toxicity should be considered in therape...
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改进两性霉素 B 靶向给药和活性的纳米技术进展(2011-2023 年):系统综述
两性霉素 B(AmB)是一种广谱、有效的治疗药物,但它的毒性和溶解性有严重的副作用。因此,在治疗过程中应考虑降低其毒性。
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来源期刊
Nanotoxicology
Nanotoxicology 医学-毒理学
CiteScore
10.10
自引率
4.00%
发文量
45
审稿时长
3.5 months
期刊介绍: Nanotoxicology invites contributions addressing research relating to the potential for human and environmental exposure, hazard and risk associated with the use and development of nano-structured materials. In this context, the term nano-structured materials has a broad definition, including ‘materials with at least one dimension in the nanometer size range’. These nanomaterials range from nanoparticles and nanomedicines, to nano-surfaces of larger materials and composite materials. The range of nanomaterials in use and under development is extremely diverse, so this journal includes a range of materials generated for purposeful delivery into the body (food, medicines, diagnostics and prosthetics), to consumer products (e.g. paints, cosmetics, electronics and clothing), and particles designed for environmental applications (e.g. remediation). It is the nano-size range if these materials which unifies them and defines the scope of Nanotoxicology . While the term ‘toxicology’ indicates risk, the journal Nanotoxicology also aims to encompass studies that enhance safety during the production, use and disposal of nanomaterials. Well-controlled studies demonstrating a lack of exposure, hazard or risk associated with nanomaterials, or studies aiming to improve biocompatibility are welcomed and encouraged, as such studies will lead to an advancement of nanotechnology. Furthermore, many nanoparticles are developed with the intention to improve human health (e.g. antimicrobial agents), and again, such articles are encouraged. In order to promote quality, Nanotoxicology will prioritise publications that have demonstrated characterisation of the nanomaterials investigated.
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