Allergic diseases in Swedish school children.

N Aberg, I Engström, U Lindberg
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引用次数: 138

Abstract

The occurrence of allergic diseases in children was studied on the basis of a questionnaire sent to the parents of 20,000 school children, 7, 10 and 14 years of age, in 3 parts of Sweden with different climatic conditions. The prevalence of asthma was 2.4%, allergic rhinoconjunctivitis 7.4%, eczema 7.8% and total allergic diseases 16.9%. The prevalence of all diseases was significantly higher in the northern part of the country than in the southern parts. This geographic variation was not related to heredity, infant feeding pattern or known exposure variables other than the cold and dry climate. Parental history of allergic diseases increased the incidence in the offspring 2-9 times, with a pattern of symptom specificity and a cumulative effect of double parental history. Breast-feeding postponed the onset of allergic disease only in children with double parental history.

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瑞典学龄儿童的过敏性疾病
在向瑞典3个不同气候条件地区的2万名7岁、10岁和14岁学龄儿童的父母发送问卷的基础上,研究了儿童过敏性疾病的发生情况。哮喘患病率2.4%,变应性鼻结膜炎患病率7.4%,湿疹患病率7.8%,总变应性疾病患病率16.9%。所有疾病的流行率在该国北部都明显高于南部。这种地理差异与遗传、婴儿喂养方式或除寒冷和干燥气候外的已知暴露变量无关。父母有变应性疾病史使子代变应性疾病发生率增加2 ~ 9倍,具有症状特异性和双父母史的累积效应。母乳喂养推迟过敏疾病的发作只有在双父母史的儿童。
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