Microwave Assisted Grafting Technique for Modification of Polysaccharides

IF 17.7 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-04-24 DOI:10.2174/0113852728296687240328080900
Neetu Rajpoot, Dinesh Puri
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Abstract

A natural and renewable substrate for the synthesis of high-performance macromolecules is polysaccharides. Grafting with the use of microwaves of synthetic polymers onto natural polysaccharides is a common, adaptable, and practical method of creating materials based on polysaccharides. It eliminates all drawbacks of the traditional grafting technique, including the need for hazardous solvents and longer reaction times. Grafting yield is also increased by microwave irradiation. In fact, the employment of microwaves in polysaccharide grafting modification for diverse applications has been prompted by the growing interest in clean and environment- friendly chemistry. Furthermore, compared with their traditionally synthesized counterparts, microwavesynthesized polysaccharide copolymers frequently have greater characteristics for commercial exploitation. Moreover, for many traditional grafting processes, the necessity for an inert environment is an additional drawback, which can be overcome by microwave grafting techniques. This study focuses on the current use of microwave heating in polysaccharide grafting modifications and its further use in pharmaceutical formulations.
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用于改性多糖的微波辅助接枝技术
多糖是合成高性能大分子的天然可再生基质。利用微波将合成聚合物接枝到天然多糖上,是制造基于多糖的材料的一种常见、适应性强且实用的方法。它消除了传统接枝技术的所有缺点,包括需要使用有害溶剂和较长的反应时间。微波辐照还能提高接枝产量。事实上,微波在多糖接枝改性中的广泛应用是由于人们对清洁环保化学的兴趣日益浓厚。此外,与传统合成的多糖共聚物相比,微波合成的多糖共聚物往往具有更高的商业利用特性。此外,对于许多传统接枝工艺来说,惰性环境是一个额外的缺点,而微波接枝技术可以克服这一缺点。本研究的重点是目前微波加热在多糖接枝改性中的应用及其在药物制剂中的进一步应用。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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