A rare case of azathioprine induced anagen effluvium and plica neuropathica

M. Rijhwani, Meet D. Patel, Amrit Malik, M. Nijhawan
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Abstract

Anagen effluvium is a type of hair loss that results from a sudden decrease in the metabolic activity of the hair follicle’s matrix cells. The condition is commonly associated with cancer treatments such as chemotherapy and radiation, but can also be caused by other factors. Plica neuropathica, on the other hand, is a condition where hair on the scalp becomes irreversibly matted. It is often linked to psychiatric disturbances, poor hair care, scalp infestations, and the use of ionic surfactants in shampoos. In rare cases, it has also been associated with certain medications. Here we present a rare case of a 16-year-old female who was on azathioprine and was diagnosed with an overlap of both conditions.
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一个罕见的硫唑嘌呤诱发增生性流出和神经性斑块病病例
脱发是由于毛囊基质细胞的新陈代谢活动突然减少而导致的一种脱发。这种情况通常与化疗和放疗等癌症治疗有关,但也可能由其他因素引起。另一方面,头皮神经性脱发是指头皮上的头发不可逆转地变得枯黄。它通常与精神障碍、头发护理不当、头皮感染以及在洗发水中使用离子表面活性剂有关。在极少数情况下,它还与某些药物有关。在此,我们介绍一例罕见病例,患者是一名 16 岁女性,当时正在服用硫唑嘌呤,被诊断为这两种病症的重叠。
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