{"title":"Visible Light-Promoted Preparation of 2,3-Dihydrobenzofurans and Coumaranones","authors":"Ting-Ting Wu, Wengui Wang","doi":"10.2174/0113852728252737240327041634","DOIUrl":null,"url":null,"abstract":"\n\n2,3-Dihydrobenzofuran and coumaranone are readily available in numerous naturally occurring\ncompounds. They mostly exist in plenty of food plants and medicinal plants. Such compounds constitute a series\nof flavor components and bioactive molecules. Their preparation has been an attractive field of research. In\nthe past few decades, great efforts have been made in the preparation of the 2,3-dihydrobenzofuran structure\nthrough both metal-catalyzed and organocatalyzed ways. Visible light-promoted reactions sprang up in the early\n21st century and represent a green manner of transformations. Under the irradiation of visible light, radicals\ncould be generated under milder conditions. Thus, visible light-promoted reactions spread widely in the field of\nchemical synthesis. In recent years, visible light-promoted preparation of 2,3-dihydrobenzofuran and coumaranone\nhas been developed by different groups, including both intramolecular and intermolecular reactions. The\nbenign reaction conditions allow better functional group-tolerance and lead to diverse structures. Several reviews\non the synthesis of 2,3-dihydrobenzofuran have been reported. However, visible light-promoted approaches\nto such structures have not been well reviewed. Our review will cover the literature that has been reported\non the discovery of 2,3-dihydrobenzofuran in food and visible light-promoted preparation of 2,3-\ndihydrobenzofuran, attempting to summarize the existing methods and provide guidance to the chemists on the\npresent challenges.\n","PeriodicalId":10926,"journal":{"name":"Current Organic Chemistry","volume":null,"pages":null},"PeriodicalIF":1.7000,"publicationDate":"2024-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Organic Chemistry","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.2174/0113852728252737240327041634","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
引用次数: 0
Abstract
2,3-Dihydrobenzofuran and coumaranone are readily available in numerous naturally occurring
compounds. They mostly exist in plenty of food plants and medicinal plants. Such compounds constitute a series
of flavor components and bioactive molecules. Their preparation has been an attractive field of research. In
the past few decades, great efforts have been made in the preparation of the 2,3-dihydrobenzofuran structure
through both metal-catalyzed and organocatalyzed ways. Visible light-promoted reactions sprang up in the early
21st century and represent a green manner of transformations. Under the irradiation of visible light, radicals
could be generated under milder conditions. Thus, visible light-promoted reactions spread widely in the field of
chemical synthesis. In recent years, visible light-promoted preparation of 2,3-dihydrobenzofuran and coumaranone
has been developed by different groups, including both intramolecular and intermolecular reactions. The
benign reaction conditions allow better functional group-tolerance and lead to diverse structures. Several reviews
on the synthesis of 2,3-dihydrobenzofuran have been reported. However, visible light-promoted approaches
to such structures have not been well reviewed. Our review will cover the literature that has been reported
on the discovery of 2,3-dihydrobenzofuran in food and visible light-promoted preparation of 2,3-
dihydrobenzofuran, attempting to summarize the existing methods and provide guidance to the chemists on the
present challenges.
期刊介绍:
Current Organic Chemistry aims to provide in-depth/mini reviews on the current progress in various fields related to organic chemistry including bioorganic chemistry, organo-metallic chemistry, asymmetric synthesis, heterocyclic chemistry, natural product chemistry, catalytic and green chemistry, suitable aspects of medicinal chemistry and polymer chemistry, as well as analytical methods in organic chemistry. The frontier reviews provide the current state of knowledge in these fields and are written by chosen experts who are internationally known for their eminent research contributions. The Journal also accepts high quality research papers focusing on hot topics, highlights and letters besides thematic issues in these fields. Current Organic Chemistry should prove to be of great interest to organic chemists in academia and industry, who wish to keep abreast with recent developments in key fields of organic chemistry.