Tuning NaCo(II) Bimetallic Cooperativity to Perform Co–H Exchange / C–F Bond Activation Processes in Polyfluoroarenes

IF 17.7 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-04-24 DOI:10.2533/chimia.2024.238

Alessandra Logallo, Eva Hevia

引用次数: 0

Abstract

Recent advances in cooperative chemistry have shown the potential of heterobimetallic complexes combining an alkali-metal with an earth abundant divalent transition metal for the functionalisation of synthetically relevant aromatic molecules via deprotonative metalation. Pairing sodium with cobalt (II), here we provide an overview of the reactivity of bimetallic [NaCo(HMDS)3] [HMDS = N(SiMe3)2] towards C-H and C-F functionalisation of a wide range of perfluorinated molecules. These studies also uncover the enormous potential of this heterobimetallic base to perform Co-H exchanges with excellent selectivity and exceptional stoichiometric control as well as shedding light on the key role played by the alkali-metal.

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调谐 NaCo(II) 双金属合作性以执行多氟烯中的 Co-H 交换/C-F 键活化过程

合作化学领域的最新进展表明，碱金属与土含量丰富的二价过渡金属结合的异双金属配合物具有通过去质子金属化作用对合成相关的芳香族分子进行官能化的潜力。将钠与钴（II）配对，我们在此概述了双金属 [NaCo(HMDS)3] [HMDS = N(SiMe3)2] 对多种全氟分子的 C-H 和 C-F 功能化反应。这些研究还揭示了这种杂多双金属基在进行 Co-H 交换方面的巨大潜力，具有极佳的选择性和卓越的化学计量控制能力，并阐明了碱金属所起的关键作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.