Aleksander H. Erga, Anastasia Ushakova, Maria Elstad, Elise Constance Fodstad, Anna Belfrage
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引用次数: 0
Abstract
OBJECTIVE
This longitudinal cohort study aims to investigate the relationship between self-reported childhood maltreatment (CM) and the retrospective trajectory of substance use, mental health, and satisfaction with life in individuals with substance use disorders.
METHODS
One hundred eleven treatment-seeking individuals with substance use disorder were recruited from clinical settings and monitored prospectively for 6 years. The participants' substance use, mental health, and satisfaction with life were assessed using standardized measures. Cluster analysis divided the cohort into two groups-low CM and high CM-based on their scores on the Childhood Trauma Questionnaire Short Form at year 6. Mixed-effects linear models were fitted to assess the association between longitudinal scores on drug use, mental health, and satisfaction with life and CM group.
RESULTS
Most participants (92%) reported at least 1 CM. Out of all participants, 36% were categorized into the high-CM group, while 59% were categorized into the low-CM group. CM group was not associated with the amount of substance or alcohol use. CM group was significantly associated with the longitudinal course of mental health and life satisfaction.
CONCLUSIONS
This study underscores the association between self-reported CM and mental health and life satisfaction in patients with substance use disorder. Our results may imply an increased risk of adverse outcomes in patients with high levels of CM, while bearing in mind that both current and retrospective mental health and substance use problems can influence the accuracy of recalling CM.
目的这项纵向队列研究旨在调查自我报告的童年虐待(CM)与药物使用障碍患者的药物使用、心理健康和生活满意度的回顾性轨迹之间的关系。方法从临床环境中招募了 111 名寻求治疗的药物使用障碍患者,并对他们进行了为期 6 年的前瞻性监测。采用标准化方法对参与者的药物使用、心理健康和生活满意度进行了评估。聚类分析根据参与者在第 6 年时童年创伤问卷简表的得分,将他们分为两组--低 CM 组和高 CM 组。混合效应线性模型用于评估药物使用、心理健康和生活满意度的纵向得分与 CM 组之间的关系。在所有参与者中,36%被归入高CM组,59%被归入低CM组。CM组与药物或酒精使用量无关。结论:本研究强调了药物使用障碍患者自我报告的 CM 与心理健康和生活满意度之间的关系。我们的研究结果可能意味着CM水平高的患者出现不良后果的风险增加,同时也要考虑到当前和回顾性的精神健康和药物使用问题会影响CM回忆的准确性。
期刊介绍:
Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance.
Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.