Schizophrenia and schizoaffective disorder: Length of stay and associated factors

IF 17.7 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-04-22 DOI:10.4102/sajpsychiatry.v30i0.2237
Ladawa Y. Goga, B. Marais
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Abstract

Background: Patients with schizophrenia and schizoaffective disorder often require longer admissions.Aim: To explore length of stay (LOS) and associated factors of patients with schizophrenia and schizoaffective disorder, admitted to a public sector specialised psychiatric hospital, over a 4-year period.Setting: The study was conducted at Tara Hospital in Johannesburg.Methods: A retrospective record review of 367 adult schizophrenia and schizoaffective disorder patients admitted between 01 January 2015 and 31 December 2018. Average LOS was calculated and the proportion of short-stay ( 30 days), medium-stay (31–90 days) and long-stay ( 90 days) admissions determined. Sociodemographic, clinical and admission outcome data were collected and analysed from a randomly selected subset of patients in each LOS category.Results: Mean LOS was 128 days (median 87, interquartile range [IQR] 49–164, range 0–755 days). A significantly greater proportion had long-stay admissions (p 0.001). Male gender (p = 0.018), being unmarried (p = 0.006), treatment resistant (p 0.001) and on clozapine (p = 0.009) were factors found to have a significant association with long-stay admissions. Rates of unemployment ( 80%), comorbid substance use disorders ( 40%), medical illnesses ( 40%), antipsychotic polypharmacy ( 40%) and readmissions ( 80%) were high. Most ( 80%) were discharged.Conclusion: Long-stay admissions were frequently required for patients with schizophrenia and schizoaffective disorder admitted to Tara Hospital.Contribution: This study highlights factors associated with long-stay admissions in patients with schizophrenia and schizoaffective disorder. More research is needed into whether increased access to community-based services, such as residential and daycare facilities, outpatient substance rehabilitation programmes and dual diagnosis clinics, could translate into shorter admissions, less frequent relapses and improved outcomes in this population.
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精神分裂症和分裂情感障碍:住院时间和相关因素
背景:精神分裂症和情感分裂症患者通常需要较长的入院时间:目的:探讨一家公立精神病专科医院四年来收治的精神分裂症和情感分裂症患者的住院时间(LOS)及相关因素:研究在约翰内斯堡的塔拉医院进行:对2015年1月1日至2018年12月31日期间收治的367名成年精神分裂症和分裂情感障碍患者进行回顾性记录审查。计算平均住院日,并确定短期住院(30 天)、中期住院(31-90 天)和长期住院(90 天)的比例。从每个住院时间类别中随机抽取一组患者,收集并分析其社会人口学、临床和入院结果数据:平均住院日为 128 天(中位数 87 天,四分位数间距 [IQR] 49-164 天,范围 0-755 天)。长期住院患者的比例明显更高(P 0.001)。研究发现,男性(p = 0.018)、未婚(p = 0.006)、耐药(p 0.001)和服用氯氮平(p = 0.009)等因素与长期住院有显著关联。失业率(80%)、合并药物使用障碍(40%)、内科疾病(40%)、服用抗精神病药物(40%)和再入院率(80%)都很高。大多数患者(80%)已经出院:结论:塔拉医院收治的精神分裂症和分裂情感障碍患者经常需要长期住院:本研究强调了精神分裂症和情感分裂症患者长期住院的相关因素。我们需要开展更多的研究,以了解更多的社区服务(如寄宿和日托设施、门诊物质康复计划和双重诊断诊所)是否能缩短住院时间、减少复发频率并改善这类人群的治疗效果。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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