Is there a “renal-pulmonary syndrome” in rheumatoid arthritis?

Modern Rheumatology Journal Pub Date : 2024-04-19 DOI:10.14412/1996-7012-2024-2-51-55

A. V. Gordeev, E. Galushko, E. V. Matyanova, E. V. Pozhidaev, E. Zotkin, A. Lila

{"title":"Is there a “renal-pulmonary syndrome” in rheumatoid arthritis?","authors":"A. V. Gordeev, E. Galushko, E. V. Matyanova, E. V. Pozhidaev, E. Zotkin, A. Lila","doi":"10.14412/1996-7012-2024-2-51-55","DOIUrl":null,"url":null,"abstract":"Objective: to compare the course of “rheumatoid disease” in multimorbid patients with and without interstitial lung disease (ILD).Material and methods. Two groups were formed of 1034 patients with active rheumatoid arthritis (RA) who met the 2010 ACR/EULAR criteria: one group with ILD identified by high-resolution computed tomography of the lungs (n=82) and another – without ILD (n=900). In all patients, estimated glomerular filtration rate (eGFR) was determined using the Cockroft–Gault formula. The presence and stage of chronic kidney disease (CKD) was assessed depending on the eGFR level: stage I CKD was diagnosed in eGFR <89 ml/min, stage II (subclinical) – 60<eGFR <89 ml/min, stage IIIa (clinical) – 45<eGFR<59 ml/min and IIIb – 30<eGFR<45 ml/min.Results and discussion. Arterial hypertension (p=0.004), cerebrovascular disease (p=0.0001), diabetes mellitus (p=0.04), obesity, psoriasis (p=0.009) and stage II–III CKD (p=0.04) were more frequently observed in the group with ILD.Conclusion. The combination of CKD and ILD frequently found in patients with RA and the known similarity and close interrelationship of the pathogenesis of these diseases, suggest a type of “renal-pulmonary syndrome” associated with a specific variant of RA.","PeriodicalId":18651,"journal":{"name":"Modern Rheumatology Journal","volume":" 17","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Modern Rheumatology Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.14412/1996-7012-2024-2-51-55","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

Abstract

Objective: to compare the course of “rheumatoid disease” in multimorbid patients with and without interstitial lung disease (ILD).Material and methods. Two groups were formed of 1034 patients with active rheumatoid arthritis (RA) who met the 2010 ACR/EULAR criteria: one group with ILD identified by high-resolution computed tomography of the lungs (n=82) and another – without ILD (n=900). In all patients, estimated glomerular filtration rate (eGFR) was determined using the Cockroft–Gault formula. The presence and stage of chronic kidney disease (CKD) was assessed depending on the eGFR level: stage I CKD was diagnosed in eGFR <89 ml/min, stage II (subclinical) – 60

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

类风湿性关节炎是否存在 "肾肺综合征"？

目的：比较患有和未患有间质性肺病（ILD）的多病种患者的 "类风湿病 "病程。将符合2010年ACR/EULAR标准的1034名活动性类风湿性关节炎（RA）患者分为两组：一组通过高分辨率肺部计算机断层扫描确定患有间质性肺病（82人），另一组没有间质性肺病（900人）。所有患者的估计肾小球滤过率（eGFR）均采用 Cockroft-Gault 公式测定。根据 eGFR 水平评估慢性肾脏病（CKD）的存在和分期：eGFR <89 ml/min，诊断为 I 期 CKD；II 期（亚临床）- 60

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Modern Rheumatology Journal

自引率

0.00%

发文量