Exploring Small-Molecule Inhibitors Targeting MAPK Pathway Components: Focus on ERK, MEK1, and MEK2 Kinases in Cancer Treatment

IF 1.4 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY Chemical Biology Letters Pub Date : 2024-04-18 DOI:10.62110/sciencein.cbl.2024.v11.659
Tuhin Mukherjee, Satyajit Mohanty, Jasleen Kaur, Mayukh Das, Krishnendu Adhikary, Prity Chatterjee, Rajkumar Maiti
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探索针对 MAPK 通路成分的小分子抑制剂:聚焦癌症治疗中的 ERK、MEK1 和 MEK2 激酶
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来源期刊
Chemical Biology Letters
Chemical Biology Letters Medicine-Biochemistry (medical)
CiteScore
8.00
自引率
26.10%
发文量
27
期刊介绍: The Chemical Biology Letter is an international journal that provides a rapid forum for publication of quality original research at the interface of chemistry and biology. Chemical biology letters covers the scientific ideas and approaches of chemistry, biology and allied interdisciplinary areas such as medicinal chemistry, drug discovery, drug delivery, biosensor, protein chemistry, biological chemistry, biomolecules, bio-technology, biomedical, molecular biology and other allied areas covering chemistry and biology for the better understanding of biological phenomenon at molecular level. The journal accepts research articles from the community of chemical biologists.
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DNA-protein crosslinks are key to platinum-based chemotherapeutic cytotoxicity Exploring Small-Molecule Inhibitors Targeting MAPK Pathway Components: Focus on ERK, MEK1, and MEK2 Kinases in Cancer Treatment Remodeling of membrane lipid homeostasis in azole resistant isolates of Candida albicans Synthesis and biological evaluation of Trifluoromethoxyphenyl Indole Carboxamide analogs, ADME and toxicity prediction Correlation of Thyroid Stimulating hormone and Liver function test in Hypothyroid and Euthyroid subjects
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