Effect of special types of bread with select herbal components on postprandial glucose levels in diabetic patients

Drasko M Gostiljac, Srdjan S Popovic, Vesna Dimitrijevic-Sreckovic, Sasa M Ilic, Jelena A Jevtovic, Dragan M Nikolic, Ivan A Soldatovic
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Abstract

BACKGROUND Nutrition recommendations in patients with type 2 diabetes mellitus (T2DM) are to consume rye or integral bread instead of white bread. A positive effect on glucoregulation has been achieved by enriching food with various biologically active substances of herbal origin, so we formulated an herbal mixture that can be used as a supplement for a special type of bread (STB) to achieve better effects on postprandial glucose and insulin levels in patients with T2DM. AIM To compare organoleptic characteristics and effects of two types of bread on postprandial glucose and insulin levels in T2DM patients. METHODS This trial included 97 patients with T2DM. A parallel group of 16 healthy subjects was also investigated. All participants were given 50 g of rye bread and the same amount of a STB with an herbal mixture on 2 consecutive days. Postprandial blood glucose and insulin levels were compared at the 30th, 60th, 90th and 120th min. A questionnaire was used for subjective estimation of the organoleptic and satiety features of the two types of bread. RESULTS Compared to patients who consumed rye bread, significantly lower postprandial blood glucose and insulin concentrations were found in T2DM patients who consumed STB. No relevant differences were found among the healthy subjects. Subjectively estimated organoleptic and satiety characteristics are better for STB than for rye bread. CONCLUSION STB have better effects than rye bread on postprandial glucoregulation in T2DM patients. Subjectively estimated organoleptic and satiety characteristics are better for STB than for rye bread. Therefore, STB can be recommended for nutrition in T2DM patients.
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含有精选草药成分的特殊类型面包对糖尿病患者餐后血糖水平的影响
背景 2 型糖尿病(T2DM)患者的营养建议是食用黑麦面包或积分面包,而不是白面包。因此,我们配制了一种草药混合物,可作为一种特殊类型面包(STB)的补充剂,从而对 T2DM 患者餐后血糖和胰岛素水平产生更好的影响。目的 比较两种面包的感官特征及其对 T2DM 患者餐后血糖和胰岛素水平的影响。方法 该试验包括 97 名 T2DM 患者。同时还对 16 名健康受试者进行了调查。所有参与者连续两天分别食用 50 克黑麦面包和等量的含草药混合物的 STB。比较了第 30、60、90 和 120 分钟的餐后血糖和胰岛素水平。使用问卷对两种面包的感官和饱腹感进行主观评估。结果 与食用黑麦面包的患者相比,食用 STB 的 T2DM 患者餐后血糖和胰岛素浓度明显较低。健康受试者之间没有发现相关差异。STB 的主观感官和饱腹感特征优于黑麦面包。结论 STB 比黑麦面包对 T2DM 患者餐后血糖调节的效果更好。STB 的主观感官和饱腹感特征优于黑麦面包。因此,STB 可推荐用于 T2DM 患者的营养。
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