Inclusion body myositis

J. Warman-Chardon, Ari Breiner, P. Bourque
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Abstract

Weakness is often asymmetrical in contrast to polymyositis. Fatigue and exercise intolerance are common but not with shortness of breath and the respiratory muscles are usually spared. Dysphagia is problematic in 40-50% of patients. Limb weakness is not inevitable and weakness of erector spinae and 'droopy neck' can be the presentation. Muscle pain and cramps are uncommon but may occur. Sensory or autonomic changes only tend to occur if there is also a concurrent polyneuropathy, such as may occur with diabetes.
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包涵体肌炎
与多发性肌炎相比,虚弱往往是不对称的。疲劳和运动不耐受很常见,但不伴有气短,呼吸肌通常不受影响。40%-50%的患者会出现吞咽困难。肢体无力并非不可避免,竖脊肌无力和 "颈部下垂 "也可能是表现形式。肌肉疼痛和痉挛并不常见,但也可能发生。只有同时伴有多发性神经病变(如糖尿病)时,才会出现感觉或自主神经变化。
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