Evaluation of Improved Imaging Properties with Tungsten-Based Parallel-Hole Collimators: A Monte Carlo Study

IF 0.6 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING World Journal of Nuclear Medicine Pub Date : 2024-04-12 DOI:10.1055/s-0044-1786165
Jalil Pirayesh Islamian, M. Ljungberg
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Abstract

Objectives The purpose of a parallel-hole collimator in a scintillation camera system is to transmit only those photons that have an emission angle close to the direction of the hole. This makes it possible to receive spatial information about the origin of the emission, that is, radioactivity decay. The dimension, shape, and intrahole thickness determine the spatial resolution and, by a tradeoff, sensitivity. The composition of the collimator material also plays an important role in determining a proper collimator. In this study, we compared tungsten alloys as a potential collimator material replacement for the conventional lead antimony material used in most of the current camera systems. Materials and Methods Monte Carlo simulations of a commercial scintillation camera system with low energy high resolution (LEHR), medium-energy (ME), and high-energy (HE) collimators of lead, tungsten, and tungsten-based alloy were simulated for different I-131, Lu-177, I-123, and Tc-99m sources, and a Deluxe rod phantom using the SIMIND Monte Carlo code. Planar images were analyzed regarding spatial resolution, image contrast in a cold source case, and system sensitivity for each collimator configuration. The hole dimensions for the three collimators were those specified in the vendor's datasheet. Results Using Pb, W, and tungsten alloy (Wolfmet) as collimator materials, the full width at half maximum (FWHM) measures for total counts (T) for LEHR with Tc-99m source (6.9, 6.8, and 6.8 mm), for ME with Lu-177 source (11.7, 11.5, and 11.6 mm), and for HE with I-131 (6.2, 13.1, and 13.1 mm) were obtained, and the system sensitivities were calculated as 89.9, 86.1, and 89.8 cpsT/MBq with Tc-99m source; 42.7, 17.4, and 20.9 cpsT/MBq with Lu-177 source; and 40.1, 69.7, and 77.4 cpsT/MBq with I-131 source. The collimators of tungsten and tungsten alloy (97.0% W, 1.5% Fe, 1.5% Ni) provided better spatial resolution and improved image contrast when compared with conventional lead-based collimators. This was due to lower septal penetration. Conclusion The results suggest that development of a new set of ME and HE tungsten and tungsten alloy collimators could improve imaging of I-131, Lu-177, and I-123.
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评估钨基平行孔准直器的改进成像特性:蒙特卡罗研究
目的闪烁照相机系统中平行孔准直器的作用是只传输发射角接近孔方向的光子。这样就可以接收到有关发射源(即放射性衰变)的空间信息。孔的尺寸、形状和孔内厚度决定了空间分辨率和灵敏度。准直器材料的成分在确定合适的准直器方面也起着重要作用。在这项研究中,我们比较了钨合金作为准直器材料的潜在替代品,以取代目前大多数照相机系统中使用的传统锑铅材料。材料与方法 使用 SIMIND 蒙特卡洛代码,针对不同的 I-131、Lu-177、I-123 和 Tc-99m 源以及 Deluxe 杆模型,对商用闪烁照相机系统的低能高分辨率(LEHR)、中能(ME)和高能(HE)准直器(铅、钨和钨基合金)进行了蒙特卡洛模拟。分析了平面图像的空间分辨率、冷源情况下的图像对比度以及每种准直器配置的系统灵敏度。三个准直器的孔尺寸均为供应商数据表中指定的尺寸。结果 使用铅、钨和钨合金(Wolfmet)作为准直器材料,使用锝-99m 源的 LEHR(6.9、6.8 和 6.8 毫米)、使用 Lu-177 源的 ME(11.7、11.5 和 11.计算得出的系统灵敏度分别为:Tc-99m 源 89.9、86.1 和 89.8 cpsT/MBq;Lu-177 源 42.7、17.4 和 20.9 cpsT/MBq;I-131 源 40.1、69.7 和 77.4 cpsT/MBq。与传统的铅基准直器相比,钨和钨合金(97.0% W、1.5% Fe、1.5% Ni)准直器的空间分辨率更高,图像对比度更好。这是因为隔膜穿透力较低。结论 结果表明,开发一套新的 ME 和 HE 钨及钨合金准直器可改善 I-131、Lu-177 和 I-123 的成像。
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来源期刊
World Journal of Nuclear Medicine
World Journal of Nuclear Medicine RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
自引率
16.70%
发文量
118
审稿时长
48 weeks
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