Predictors of nutritional recovery time in children aged 6-59 months with severe acute malnutrition in Sofala Province, Mozambique: survival analysis approach.

Audêncio Victor, Bélio Castro Antônio, Ana Raquel Manuel Gotine, Manuel Mahoche, Sancho Pedro Xavier, Osiyallê Akanni Silva Rodrigues, Andrêa Ferreira, Patrícia H. Rondó
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Abstract

BACKGROUND Malnutrition is a public health problem that affects physical and psychosocial well-being. It manifests as a rapid deterioration in nutritional status and bilateral edema due to inadequate food intake or illness. METHODS This study is a retrospective cohort of 1208 children with severe acute malnutrition (SAM) in Sofala Province from 2018 to 2022. It includes hospitalized children aged 6-59 months with SAM and related complications. The dependent variable is recovery, and the independent variables include age, sex of the child, vomiting, dehydration, hypoglycemia, nutritional edema and anthropometry. Survival curves were plotted using the Kaplan-Meier method, and bivariable and multivariable Cox regression analyses were performed. RESULTS The crude analysis revealed significant factors for nutritional recovery in children with SAM, including age, weight, height, malaria, diarrhea and dehydration. Children under 24 months had a 28% lower likelihood of recovery. Weight below 6.16 kg decreased the likelihood by 2%, and height above 71.1 cm decreased it by 20%. Conversely, malaria, diarrhea and dehydration increased the likelihood of recovery. However, after adjustment, only diarrhea remained a significant predictor of nutritional recovery. CONCLUSION This study found that diarrhea is a predictor of nutritional recovery in children with SAM.
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莫桑比克索法拉省 6-59 个月严重急性营养不良儿童营养恢复时间的预测因素:生存分析方法。
背景营养不良是一个影响身心健康的公共卫生问题。它表现为因食物摄入不足或疾病导致的营养状况迅速恶化和双侧水肿。方法本研究是一项回顾性队列研究,涉及索法拉省 2018 年至 2022 年期间 1208 名患有严重急性营养不良(SAM)的儿童。研究对象包括患有 SAM 及相关并发症的 6-59 个月住院儿童。因变量为康复,自变量包括年龄、儿童性别、呕吐、脱水、低血糖、营养性水肿和人体测量。结果粗略分析显示,影响萨姆病患儿营养恢复的重要因素包括年龄、体重、身高、疟疾、腹泻和脱水。24 个月以下的儿童康复的可能性降低了 28%。体重低于 6.16 千克的儿童康复可能性降低 2%,身高超过 71.1 厘米的儿童康复可能性降低 20%。相反,疟疾、腹泻和脱水会增加康复的可能性。然而,经过调整后,只有腹泻仍是营养恢复的重要预测因素。
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