Atrial Fibrillation and Chronic Kidney Disease: Aetiology and Management

B. Sidhu, A. Mavilakandy, Katherine L Hull, I. Koev, Zakariyya Vali, James O. Burton, G. A. Ng
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Abstract

Chronic kidney disease (CKD) and atrial fibrillation (AF) are associated with significant cardiovascular morbidity and mortality. Recent studies have highlighted an increased prevalence and incidence of AF in patients with CKD. This article aims to provide a comprehensive review of current management strategies and considerations of treating atrial fibrillation with concomitant CKD. Potential electrophysiological mechanisms between AF and CKD are explored. Current evidence and literature focusing on pharmacological rate and rhythm control along with procedural intervention is reviewed and presented. The management of AF and CKD together is complex, but particularly pertinent when considering the close cyclical relationship in the progression of both diseases.
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心房颤动与慢性肾病:病因和管理
慢性肾脏病(CKD)和心房颤动(AF)与心血管疾病的发病率和死亡率密切相关。最近的研究表明,慢性肾脏病患者心房颤动的患病率和发病率均有所上升。本文旨在全面综述目前治疗伴有慢性肾脏病的心房颤动的管理策略和注意事项。文章探讨了房颤与慢性肾脏病之间潜在的电生理机制。回顾并介绍了以药物控制心率和心律以及程序干预为重点的当前证据和文献。心房颤动和慢性肾脏病的综合治疗非常复杂,但考虑到这两种疾病在发展过程中的密切周期性关系,其治疗尤为重要。
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