"Trend" Statement Use in the Orthopaedic Literature.

Andrew J Luzzi, Natalia Czerwonka, Brandon L Rogalski, Michael L Knudsen, William N. Levine
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Abstract

INTRODUCTION For research to effectively guide clinical decision making, appropriate interpretation of data is paramount. The P-value is a useful tool for guiding the interpretation of data. However, despite its utility, the P-value is not without limitations. Of particular concern is the use of "trend statements" to describe non-statistically significant findings, a practice which introduces subjectivity and variability into data interpretation and can lead to the drawing of undue conclusions. METHODS An audit of original research articles published from January 2022 to December 2022 in four high-impact orthopaedic journals was conducted. The selected journals were queried to identify instances in which a non-statistically significant result was labeled as a "trend." The use of trend statements and associated information was recorded and analyzed. RESULTS One thousand two hundred sixty articles were included in the analysis. 81 articles (6.4%) included a trend statement to describe a non-statistically significant result. Only two articles (2.5%) formally defined what constituted a trend. In 28.8% of cases, the associated P-value was > 0.10. DISCUSSION Trend statements are used to describe non-statistically significant findings with moderate frequency in the orthopaedic literature. Given the potentially misleading effects of trend statements, efforts should be made to mitigate their use. If trend statements are to be used, attention should be paid to defining what constitutes a "trend", explicitly acknowledging the lack of statistical significance of the finding to which the trend statement refers, and avoiding drawing undue conclusions from non-statistically significant data.
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矫形外科文献中 "趋势 "声明的使用。
引言 为使研究能有效地指导临床决策,对数据进行适当的解释至关重要。P 值是指导数据解释的有用工具。然而,尽管 P 值很有用,它也并非没有局限性。尤其值得关注的是使用 "趋势声明 "来描述非统计学意义的研究结果,这种做法在数据解读中引入了主观性和可变性,可能导致得出不恰当的结论。方法对 2022 年 1 月至 2022 年 12 月期间在四种影响力较大的骨科期刊上发表的原创研究文章进行了审核。对所选期刊进行了查询,以确定将无统计学意义的结果标注为 "趋势 "的情况。对趋势声明和相关信息的使用情况进行了记录和分析。有 81 篇文章(6.4%)使用了趋势声明来描述非统计显著性结果。只有两篇文章(2.5%)正式定义了什么是趋势。在 28.8% 的情况下,相关的 P 值大于 0.10。讨论在骨科文献中,趋势声明被用于描述非统计学意义结果的频率并不高。鉴于趋势声明可能产生误导作用,应努力减少其使用。如果要使用趋势声明,应注意定义什么是 "趋势",明确承认趋势声明所涉及的发现缺乏统计学意义,并避免从无统计学意义的数据中得出不恰当的结论。
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