Serial Excision Technique to Reduce Cicatricial Alopecia

IF 17.7 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-04-09 DOI:10.1159/000538397
M. Benez, Ana Luísa Alves, Lucas Emmels, Adriana Dornelas, Guillermo Loda
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Abstract

Introduction: Cicatricial alopecia (CA) poses a challenge for dermatologists due to irreversible hair follicle damage. While pharmacological treatments offer limited efficacy, surgical interventions aim to improve aesthetic outcomes. This article explores the serial excision technique (SET) as a viable option for stable cases of inflammatory CA. Case Report/Case Presentation: Three adult females with different forms of CA underwent staged surgeries to correct CA patches. Procedures included different incision and closure methods based on individual characteristics such as age, type and extent of alopecia, location, and tissue mobility in the scarred area. Discussion: CA significantly impacts patients’ quality of life, demanding comprehensive treatment approaches. SET emerges as an encouraging possibility for stable cases, providing notable cosmetic improvements and enhancing patients’ well-being. This technique offers cost-effective benefits with potential standalone efficacy or in combination with hair transplantation, providing promising outcomes for individuals with CA.
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减少斑秃的连续切除技术
导言:由于毛囊损伤不可逆,毛囊角化性脱发(CA)给皮肤科医生带来了挑战。药物治疗的疗效有限,而手术干预则旨在改善美学效果。本文探讨了序列切除技术(SET),将其作为炎症性秃发稳定期病例的一种可行选择。病例报告/病例介绍:三名患有不同形式 CA 的成年女性接受了分期手术,以矫正 CA 斑块。手术方法包括根据个体特征(如年龄、脱发类型和程度、位置以及瘢痕区域组织的流动性)采用不同的切口和闭合方法。讨论CA 严重影响了患者的生活质量,需要采取综合治疗方法。对于病情稳定的病例,SET 是一种令人鼓舞的治疗方法,它能明显改善外观,提高患者的生活质量。这项技术具有成本效益,可单独使用,也可与毛发移植手术结合使用,为 CA 患者带来良好的治疗效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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