Accuracy of foot length measurement for gestational age assessment in neonates: a prospective observational study in Central India

Asmita Singhal, A. Agrawal, Rashmi Parihar, Nency Sahu, Jaya Upadhyay
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Abstract

Background: Gestational age (GA) is a critical-factors in the decision making and predicting mortality and morbidities of neonates. In low resource settings where affordability and availability of first trimester scan is limited, assessment is often done by postnatal methods like expanded new Ballard score (ENBS) which are often clinical skill dependent and complex. Hence, there is a need of a simple and cost-effective method which can be readily adopted by frontline health care workers at periphery. One such method is assessment of foot length (FL). Methods: This prospective cross-sectional study was conducted in the level 3 NICU of Central India over a period of 18 months. Included neonates were assessed for GA by measuring FL by vernier calliper within 48 hours of birth and its validity was tested against ENBS as reference standard. Other anthropometric measurements like birth weight, head circumference and length were obtained within 48 hours of birth. Results: Total 700 neonates were included in the study. For, determining preterm newborn, the potential cut-off of FL of ≤6.86 cm, with a sensitivity of 94.6% and specificity of 73.8%. The area under ROC (receiver operating characteristic) curve is 0.92. Conclusions: FL measurement is a cost-effective and time-saving simple intervention that can facilitate early identification of preterm newborns as well as help in initiating timely interventions and hence improving neonatal outcomes in resource-poor settings.
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新生儿足长测量用于胎龄评估的准确性:印度中部地区的前瞻性观察研究
背景:胎龄(GA)是决定和预测新生儿死亡率和发病率的关键因素。在资源匮乏的环境中,人们的经济承受能力和第一孕期扫描的可用性都很有限,因此通常采用扩大新巴拉德评分(ENBS)等产后方法进行评估,而这些方法往往依赖于临床技能且非常复杂。因此,需要一种简单而又经济有效的方法,让外围的一线医护人员能够随时采用。评估足长(FL)就是这样一种方法:这项前瞻性横断面研究在印度中部的三级新生儿重症监护室进行,历时 18 个月。在新生儿出生 48 小时内,用游标卡尺测量足长,对其进行 GA 评估,并以 ENBS 作为参考标准测试其有效性。其他人体测量数据,如出生体重、头围和身长也在出生后 48 小时内获得:研究共纳入了 700 名新生儿。对于早产新生儿,FL≤6.86 厘米的潜在临界值的灵敏度为 94.6%,特异性为 73.8%。ROC(接收者操作特征)曲线下的面积为 0.92:FL测量是一项成本效益高、节省时间的简单干预措施,有助于早期识别早产新生儿,并帮助及时启动干预措施,从而改善资源匮乏地区的新生儿预后。
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