Effect of Robotic Inferior Mesenteric Artery Ligation Level on Low Anterior Resection Syndrome in Rectum Cancer.

Rıdvan Yavuz, O. Aras, Hüseyin Çiyiltepe, Tebessüm Çakır, C. Ö. Ensari, İsmail Gömceli
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Abstract

Background: Life expectancy of patients with rectal cancer is increasing day by day with innovative treatments. Low anterior resection syndrome (LARS), which disrupts the comfort of life in these patients, has become a serious problem. We aimed to evaluate the effect of high ligation (HL) and low ligation (LL) techniques on LARS in rectal cancer surgery performed with the robotic method. Materials and Methods: The data of patients diagnosed with mid-distal rectal cancer between 2016 and 2021 who underwent robotic low anterior resection by the same team in the same center with neoadjuvant chemoradiotherapy were retrospectively evaluated. Patients were divided into two groups as those who underwent HL and LL procedures. Preoperative, 8 weeks after neoadjuvant treatment, 3 and 12 months after ileostomy closure were evaluated. Results: A total of 84 patients (41 HL, 43 LL) were included in the study. There was no statistically significant difference between the demographic characteristics and pathology data of the patients. Although there was a decrease in LARS scores after neoadjuvant treatment, there was a statistically significant difference between the two groups at 3 and 12 months after ileostomy closure (P: .001, P: .015). Conclusions: In patients who underwent robotic low anterior resection, there is a statistically significant difference in the LARS score in the first 1 year with the LL technique compared with that of the HL technique, and the LL technique has superiority in reducing the development of LARS between the two oncologically indistinguishable methods.
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机器人肠系膜下动脉结扎水平对直肠癌低位前切除综合征的影响
背景:随着治疗方法的创新,直肠癌患者的预期寿命与日俱增。低位前切除综合征(LARS)破坏了这些患者的生活舒适度,已成为一个严重的问题。我们旨在评估机器人直肠癌手术中高结扎(HL)和低结扎(LL)技术对 LARS 的影响。材料与方法:回顾性评估2016年至2021年期间确诊的中段直肠癌患者的数据,这些患者由同一中心的同一团队进行了机器人低位前切除术,并接受了新辅助化放疗。患者分为 HL 和 LL 两组。分别对术前、新辅助治疗后8周、回肠造口关闭后3个月和12个月进行评估。结果研究共纳入了 84 名患者(41 名 HL,43 名 LL)。患者的人口统计学特征和病理学数据差异无统计学意义。虽然新辅助治疗后 LARS 评分有所下降,但在回肠造口术关闭后 3 个月和 12 个月,两组患者的 LARS 评分差异有统计学意义(P:.001,P:.015)。结论在接受机器人低位前切除术的患者中,LL 技术与 HL 技术相比,在头 1 年的 LARS 评分差异有统计学意义,在两种肿瘤学上无差别的方法中,LL 技术在减少 LARS 的发生方面更具优势。
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