A guide to mycetisms: a toxicological and preventive overview.

IF 2.7 3区 医学 Q3 INFECTIOUS DISEASES Medical mycology Pub Date : 2024-04-03 DOI:10.1093/mmy/myae033
M. Benvenuti, M. Zotti, S. La Maestra
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Abstract

Fungi are often considered a delicacy and are primarily cultivated and harvested, although numerous species are responsible for intoxication due to toxin content. Foodborne diseases are a significant public health concern, causing approximately 420,000 deaths and 600 million morbidities yearly, of which mushroom poisoning is one of the leading causes. Epidemiological data on non-cultivated mushroom poisoning in individual countries are often unrepresentative, as intoxication rarely requires emergency intervention. On the other hand, the lack of specialist knowledge among medical personnel about the toxicological manifestations of mushroom consumption may result in ineffective therapeutic interventions. This work aims to provide an easy-to-consult and wide-ranging tool useful for better understanding the variability of mushroom intoxications, the associated symptoms, and the main treatments for the most severe cases, given the absence of a complete species mapping tool toxic. Moreover, we establish an effective collection network that describes the incidence of mushroom poisonings by reporting the species and associated toxicological manifestations for each case. In conclusion, we highlight the need to establish appropriate primary prevention interventions, such as training the affected population and increasing consultancy relationships between mycological experts and specialised healthcare personnel.
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霉菌指南:毒理学和预防概述。
真菌通常被视为美味佳肴,主要用于栽培和收获,但许多种类的真菌因含有毒素而导致中毒。食源性疾病是一个重大的公共卫生问题,每年造成约 42 万人死亡,6 亿人发病,其中蘑菇中毒是主要原因之一。各个国家非栽培蘑菇中毒的流行病学数据往往不具代表性,因为中毒很少需要紧急干预。另一方面,医务人员对食用蘑菇的毒理学表现缺乏专业知识,可能导致治疗干预无效。由于缺乏完整的毒物物种图谱工具,这项工作旨在提供一个易于查询且范围广泛的工具,帮助人们更好地了解蘑菇中毒的变异性、相关症状以及最严重病例的主要治疗方法。此外,我们还建立了一个有效的收集网络,通过报告每个病例的物种和相关毒理学表现来描述蘑菇中毒的发生率。总之,我们强调有必要建立适当的初级预防干预措施,例如对受影响人群进行培训,增加真菌学专家和专业医护人员之间的咨询关系。
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来源期刊
Medical mycology
Medical mycology 医学-兽医学
CiteScore
5.70
自引率
3.40%
发文量
632
审稿时长
12 months
期刊介绍: Medical Mycology is a peer-reviewed international journal that focuses on original and innovative basic and applied studies, as well as learned reviews on all aspects of medical, veterinary and environmental mycology as related to disease. The objective is to present the highest quality scientific reports from throughout the world on divergent topics. These topics include the phylogeny of fungal pathogens, epidemiology and public health mycology themes, new approaches in the diagnosis and treatment of mycoses including clinical trials and guidelines, pharmacology and antifungal susceptibilities, changes in taxonomy, description of new or unusual fungi associated with human or animal disease, immunology of fungal infections, vaccinology for prevention of fungal infections, pathogenesis and virulence, and the molecular biology of pathogenic fungi in vitro and in vivo, including genomics, transcriptomics, metabolomics, and proteomics. Case reports are no longer accepted. In addition, studies of natural products showing inhibitory activity against pathogenic fungi are not accepted without chemical characterization and identification of the compounds responsible for the inhibitory activity.
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