Kolcheva Maria Andreevna, Kumirova Ella Vyacheslavovna, Gorbatykh Svetlana Valeryevna, Makhmudova Gunai Nariman, Livshits Matvey Igorevich, Chmutin Gennadiy Yegorovich, Kislyakov Alexey Nikolaevich, Umerenkov Viktor Nikolaevich, M.J. Encarnacion Ramirez, N. Montemurro
{"title":"Long-Term Survival of a Child with Atypical Teratoid-Rhabdoid Tumor and Acute Lymphoblastic Leukemia: A Case Report","authors":"Kolcheva Maria Andreevna, Kumirova Ella Vyacheslavovna, Gorbatykh Svetlana Valeryevna, Makhmudova Gunai Nariman, Livshits Matvey Igorevich, Chmutin Gennadiy Yegorovich, Kislyakov Alexey Nikolaevich, Umerenkov Viktor Nikolaevich, M.J. Encarnacion Ramirez, N. Montemurro","doi":"10.3390/surgeries5020018","DOIUrl":null,"url":null,"abstract":"Atypical teratoid-rhabdoid tumor (AT/RT) is a rare but one of the most aggressive embryonal tumors of the central nervous system (CNS), most often occurring in children under 3 years of age. AT/RT accounts for about 1–2% of all CNS neoplasms and has a very poor prognosis, high risk of secondary tumor development, recurrence and/or metastasis in patients in remission and limited therapeutic potential. The clinical manifestations are usually symptoms of increased intracranial pressure. The mainstay of tumor treatment is complex chemotherapy combined with radiation therapy. A clinical case of sequential occurrence of two cancers (AT/RT and leukemia) in a 3-year-old girl is presented.","PeriodicalId":506240,"journal":{"name":"Surgeries","volume":"566 ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Surgeries","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3390/surgeries5020018","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Atypical teratoid-rhabdoid tumor (AT/RT) is a rare but one of the most aggressive embryonal tumors of the central nervous system (CNS), most often occurring in children under 3 years of age. AT/RT accounts for about 1–2% of all CNS neoplasms and has a very poor prognosis, high risk of secondary tumor development, recurrence and/or metastasis in patients in remission and limited therapeutic potential. The clinical manifestations are usually symptoms of increased intracranial pressure. The mainstay of tumor treatment is complex chemotherapy combined with radiation therapy. A clinical case of sequential occurrence of two cancers (AT/RT and leukemia) in a 3-year-old girl is presented.
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