5-Factor Modified Frailty Index as a Predictor of Outcomes After Hemiarthroplasty or Total Hip Arthroplasty for Femoral Neck Fracture.

Andrew G Kim, Daniel Grits, Jeffrey Zhong, Austin M Chiu, Landon Reading, William A. Zuke, A. Kamath
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Abstract

INTRODUCTION Although the 5-factor modified frailty index (mFI-5) has been shown to be an independent predictor of complications after primary total hip arthroplasty (THA), its predictive value has not been evaluated in the setting of hip fracture. We therefore assessed the utility of mFI-5 score as an independent predictor of morbidity and mortality in patients who underwent THA or hemiarthroplasty for femoral neck fracture. METHODS The American College of Surgeons National Surgical Quality Improvement database was queried for all patients with femoral neck fractures treated with THA or hemiarthroplasty between 2006 and 2020. A multivariate logistic regression analysis was done using mFI-5 as a predictor while controlling for baseline demographic and clinical variables. RESULTS In total, 45,185 patients (hemiarthroplasty: 37,645; THA: 7,540) were identified. For hemiarthroplasty patients, the mFI-5 strongly predicted risk of any complication (OR, 1.1; 95% CI, 1.1 to 1.2; P < 0.001), bleeding (OR, 1.2; 95% CI, 1.1 to 1.3; P < 0.001), and readmission (OR, 1.2; 95% CI, 1.1 to 1.3; P < 0.001). For THA patients, the mFI-5 was a strong predictor of any complication (OR, 1.2; 95% CI, 1.0 to 1.3; P = 0.023), pneumonia (OR, 1.4; 95% CI, 1.0 to 2.0; P = 0.047), and readmission (OR, 1.3; 95% CI, 1.1 to 1.6; P = 0.004). DISCUSSION The mFI-5 is an independent predictor of morbidity and complications after hemiarthroplasty and THA for femoral neck fracture. Importantly, readmission risk was predicted by the mFI-5. The mFI-5 may present a valuable clinical tool for assessment of high-risk patients who might require additional resources and specialized care after femoral neck fracture.
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股骨颈骨折半关节置换术或全髋关节置换术后预后的 5 因子改良虚弱指数。
引言 虽然五因子改良虚弱指数(mFI-5)已被证明是初级全髋关节置换术(THA)后并发症的独立预测指标,但其在髋部骨折情况下的预测价值尚未得到评估。因此,我们评估了 mFI-5 评分作为股骨颈骨折接受 THA 或半髋关节置换术患者发病率和死亡率独立预测指标的实用性。方法:我们查询了美国外科学院国家外科质量改进数据库中 2006 年至 2020 年间接受 THA 或半髋关节置换术治疗的所有股骨颈骨折患者。在控制基线人口统计学和临床变量的同时,使用 mFI-5 作为预测因子进行了多变量逻辑回归分析。结果共识别出 45185 例患者(半关节成形术:37645 例;THA:7540 例)。对于半关节置换术患者,mFI-5 可强烈预测任何并发症(OR,1.1;95% CI,1.1 至 1.2;P <0.001)、出血(OR,1.2;95% CI,1.1 至 1.3;P <0.001)和再入院(OR,1.2;95% CI,1.1 至 1.3;P <0.001)的风险。对于 THA 患者,mFI-5 是任何并发症(OR,1.2;95% CI,1.0 至 1.3;P = 0.023)、肺炎(OR,1.4;95% CI,1.0 至 2.0;P = 0.047)和再入院(OR,1.讨论mFI-5是股骨颈骨折半关节成形术和THA术后发病率和并发症的独立预测指标。重要的是,mFI-5还能预测再入院风险。mFI-5可能是评估股骨颈骨折后可能需要额外资源和专门护理的高危患者的重要临床工具。
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