Disability weights for environmental noise-related health states: results of a disability weights measurement study in Europe

P. Charalampous, C. C. Maas, J. Haagsma
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Abstract

Measurement of the burden of disease using disability-adjusted life years requires disability weights to quantify health losses for non-fatal consequences of disease and injury. We aimed to obtain a set of disability weights for environmental and non-environmental noise-related health states (NOISE) using a nationally representative sample survey among the general population of four European countries; and to compare the resulting NOISE disability weights with those estimated in the Global Burden of Disease 2010 (GBD 2010) and European (EURO) disability weights measurement studies.We administered a web-based survey among a cohort of individuals from Hungary, Italy, Sweden and the Netherlands. It included paired comparison questions on 82 different health states. Each respondent performed 13 paired comparison tasks. We analysed paired comparison responses with probit regression analysis, and regression results were anchored on the disability weight scale between 0 (equivalent to full health) and 1 (equivalent to death).In total, 4056 respondents participated in the study. Comparison of the regression results from paired comparison responses for each country-specific dataset with those run on the pooled dataset showed high linear correlations (0.96–0.98, p<0.001). The resulting disability weights ranged from 0.005 for mild impairment of distance vision and mild anaemia to 0.761 for intensive care unit admission. The disability weight for moderate and severe annoyance was 0.006 and 0.011, respectively. Comparison of disability weights showed a higher correlation between EURO and NOISE disability weights (pseudo R-squared=0.955, Pearson correlation=0.954) compared with GBD 2010 and NOISE disability weights (pseudo R-squared=0.893, Pearson correlation=0.946).The NOISE disability weights are consistent and highly correlated across the four European countries. The NOISE disability weights set can be used to estimate the burden of disease attributable to noise-related outcomes across Europe.
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环境噪声相关健康状况的残疾权重:欧洲残疾权重测量研究的结果
使用残疾调整生命年衡量疾病负担需要残疾权重,以量化疾病和伤害造成的非致命后果的健康损失。我们的目标是通过在四个欧洲国家的普通人群中进行具有全国代表性的抽样调查,获得一套与环境和非环境噪声相关的健康状态(NOISE)的残疾权重;并将得出的 NOISE 残疾权重与《2010 年全球疾病负担》(GBD 2010)和欧洲(EURO)残疾权重测量研究中估计的残疾权重进行比较。调查内容包括 82 种不同健康状况的配对比较问题。每位受访者都完成了 13 项配对比较任务。我们采用 probit 回归分析法对配对比较回答进行了分析,并将回归结果锚定在 0(相当于完全健康)和 1(相当于死亡)之间的残疾权重表上。将每个国家数据集的配对比较回答的回归结果与汇总数据集的回归结果进行比较,结果显示两者具有很高的线性相关性(0.96-0.98,p<0.001)。由此得出的残疾权重从轻度远视障碍和轻度贫血的 0.005 到入住重症监护室的 0.761 不等。中度和重度烦恼的残疾权重分别为 0.006 和 0.011。残疾权重的比较显示,与 GBD 2010 和 NOISE 残疾权重(伪 R 平方=0.893,Pearson 相关性=0.946)相比,EURO 和 NOISE 残疾权重之间的相关性更高(伪 R 平方=0.955,Pearson 相关性=0.954)。NOISE 残疾权重集可用于估算整个欧洲与噪声相关的结果所造成的疾病负担。
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