{"title":"The past, the present and the promising: a report of a rare case of parathyroid carcinoma","authors":"Sarah Ruane, Pedro Oliveira","doi":"10.1016/j.mpdhp.2024.03.006","DOIUrl":null,"url":null,"abstract":"<div><p>Parathyroid carcinoma (PTC) is an uncommon endocrine neoplasm. There are well-established criteria for its diagnosis, but diligent practical application of these criteria can be challenging for even the most discerning pathologist. We report a case of PTC demonstrating classical lymphovascular invasion, and review how pathologists can confidently and effectively diagnose PTC utilising the correct morphological histopathological features, supported by a panel of immunohistochemical stains and ancillary molecular testing.</p></div>","PeriodicalId":39961,"journal":{"name":"Diagnostic Histopathology","volume":"30 6","pages":"Pages 348-350"},"PeriodicalIF":0.0000,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Diagnostic Histopathology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1756231724000483","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Parathyroid carcinoma (PTC) is an uncommon endocrine neoplasm. There are well-established criteria for its diagnosis, but diligent practical application of these criteria can be challenging for even the most discerning pathologist. We report a case of PTC demonstrating classical lymphovascular invasion, and review how pathologists can confidently and effectively diagnose PTC utilising the correct morphological histopathological features, supported by a panel of immunohistochemical stains and ancillary molecular testing.
期刊介绍:
This monthly review journal aims to provide the practising diagnostic pathologist and trainee pathologist with up-to-date reviews on histopathology and cytology and related technical advances. Each issue contains invited articles on a variety of topics from experts in the field and includes a mini-symposium exploring one subject in greater depth. Articles consist of system-based, disease-based reviews and advances in technology. They update the readers on day-to-day diagnostic work and keep them informed of important new developments. An additional feature is the short section devoted to hypotheses; these have been refereed. There is also a correspondence section.