Compare the surgical outcome of Fistulectomy and Mucoal advancement flap in perianal fistula.

Mudassar Jabeen, Shahbaz Ahmed, Nida Firdous, Samia Rasool
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Abstract

Objective: To compare the fistulectomy with mucosal advancement flap in treatment of perianal fistula in terms of mean hospital stay, frequency of anal incontinence and wound healing time. Study Design: Randomized Control Trial. Setting: Surgical OPD, DHQ and Allied Hospital, Faisalabad. Period: 1st March 2019 to 28 February 2020. Methods: Conducted on 120 (60 in each group) patients with fistula in ano presenting. Sampling technique was Non probability consecutive sampling. All the Patient age ranges from 20-55 years of either gender having perianal fistula which are low lying fistulas and with single external opening are included in study. Patients having perianal abscess, pilonidal sinus, Inflammatory bowel disease (Crohn’s disease, Ulcerative colitis) or with history of tuberculosis, HIV disease, Complex high lying fistulas with multiple external openings are excluded. Results: In our study, group A underwent fistulectomy while on group B we perform mucosal advancement flap. About 56.67%(n=34) in Group A and 50%(n=30) in Group B were between 20-40 years of age while 43.33%(n=26) in Group A and 50%(n=30) in Group B were between 41-55 years of age, mean+SD was calculated as 38.78+9.07 years and 40.12+8.89 years respectively. According to gender division 86.67%(n=52) in Group A and 78.33%(n=47) in Group B were male while 13.33%(n=8) in Group A and 21.67%(n=13) in Group B were females, mean hospital stay was calculated as 93.93+4.56 hours in Group A and 107.95+4.66 hours in Group B, p value was calculated as 0.0001 showing a significant difference between the two groups. Comparison of anal incontinence in both groups was done showing that 13.33% (n=8) in Group A and 23.33%(n=14) in Group B had anal incontinence, p value was calculated as 0.15. At one month postoperative follow-up only 4 patient (6.7%) in group A showed complete wound healing while in group B 28 patients out of 60(46.6%)showed complete wound healing, P value was calculated as 0.00167 showing a significant difference while there is no significant difference in incidence of early post-operative complications. Conclusion: We concluded that hospital stay was significantly decreased in cases with fistulectomy when compared with MAF while there was no significant difference regarding anal incontinence in both groups.
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比较肛周瘘的瘘管切除术和 Mucoal 推进瓣的手术效果。
目的从平均住院时间、肛门失禁频率和伤口愈合时间的角度,比较瘘管切除术和粘膜前移皮瓣治疗肛周瘘的效果。研究设计:随机对照试验。研究地点费萨拉巴德 DHQ 和联合医院外科门诊。时间: 2019年3月1日至2020年2月28日2019年3月1日至2020年2月28日。方法:随机对照试验对 120 名(每组 60 名)肛瘘患者进行抽样调查。抽样技术为非概率连续抽样。研究对象包括所有年龄在 20-55 岁之间、患有肛周瘘的男女患者,肛周瘘为低位瘘管,只有一个外部开口。患有肛周脓肿、念珠菌窦、炎症性肠病(克罗恩病、溃疡性结肠炎)或有结核病史、艾滋病史、有多个外部开口的复杂高位肛瘘的患者除外。研究结果在我们的研究中,A 组进行了瘘管切除术,而 B 组则进行了粘膜前移瓣手术。A组约56.67%(34人)和B组约50%(30人)的患者年龄在20-40岁之间,A组约43.33%(26人)和B组约50%(30人)的患者年龄在41-55岁之间,平均年龄+SD分别为38.78+9.07岁和40.12+8.89岁。根据性别划分,A 组中男性占 86.67%(n=52),B 组中男性占 78.33%(n=47);A 组中女性占 13.33%(n=8),B 组中女性占 21.67%(n=13);A 组平均住院时间为 93.93+4.56 小时,B 组平均住院时间为 107.95+4.66 小时。两组肛门失禁情况比较显示,A 组有 13.33%(8 人)和 B 组有 23.33%(14 人)出现肛门失禁,P 值为 0.15。在术后一个月的随访中,A 组只有 4 名患者(6.7%)的伤口完全愈合,而 B 组 60 名患者中有 28 名(46.6%)的伤口完全愈合,P 值为 0.00167,显示出显著差异,而术后早期并发症的发生率没有显著差异。结论我们得出的结论是,与 MAF 相比,肛瘘切除术患者的住院时间明显缩短,但两组患者在肛门失禁方面无明显差异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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