{"title":"Comorbilidades psiquiátricas de la dermatitis atópica","authors":"","doi":"10.1016/j.piel.2023.12.012","DOIUrl":null,"url":null,"abstract":"<div><p>Atopic dermatitis (AD) is a chronic inflammatory skin disorder with high prevalence and a significant impact on quality of life, associated with multiple comorbidities, both atopic and non-atopic. There has been a recent increase in efforts to understand the relationship between AD and this broad spectrum of comorbidities, with a notable emphasis on psychiatric conditions due to their substantial impact on quality of life. Patients with AD appear to have an increased risk of experiencing depression and anxiety, among other mental health disorders, with this risk being higher as the severity of AD increases. While in some cases, this could be explained by the presence of certain proinflammatory cytokines capable of crossing the blood-brain barrier, in the majority of cases, other factors are likely involved, such as chronic itch or sleep disorders. The objective of this review is to present the most relevant recent evidence regarding the relationship between AD and psychiatric disorders.</p></div>","PeriodicalId":20182,"journal":{"name":"Piel","volume":"39 7","pages":"Pages 428-434"},"PeriodicalIF":0.0000,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Piel","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0213925124000960","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Atopic dermatitis (AD) is a chronic inflammatory skin disorder with high prevalence and a significant impact on quality of life, associated with multiple comorbidities, both atopic and non-atopic. There has been a recent increase in efforts to understand the relationship between AD and this broad spectrum of comorbidities, with a notable emphasis on psychiatric conditions due to their substantial impact on quality of life. Patients with AD appear to have an increased risk of experiencing depression and anxiety, among other mental health disorders, with this risk being higher as the severity of AD increases. While in some cases, this could be explained by the presence of certain proinflammatory cytokines capable of crossing the blood-brain barrier, in the majority of cases, other factors are likely involved, such as chronic itch or sleep disorders. The objective of this review is to present the most relevant recent evidence regarding the relationship between AD and psychiatric disorders.
特应性皮炎（AD）是一种慢性炎症性皮肤病，发病率很高，对生活质量有很大影响，并伴有多种合并症，包括特应性和非特应性。最近，人们越来越努力地了解 AD 与这些广泛的并发症之间的关系，并特别强调精神疾病，因为这些疾病对生活质量有着重大影响。除其他精神疾病外，注意力缺失症患者患抑郁症和焦虑症的风险似乎也在增加，而且随着注意力缺失症严重程度的增加，这种风险也在增加。虽然在某些情况下，这可以用某些能够穿过血脑屏障的促炎细胞因子的存在来解释，但在大多数情况下，这可能与其他因素有关，如慢性瘙痒或睡眠障碍。本综述旨在介绍有关注意力缺失症与精神障碍之间关系的最新相关证据。
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