Therapeutic Effects of Amaranth: Analysis of the Antidiabetic Potential of the Plant.

IF 17.7 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-04-01 DOI:10.1089/jmf.2022.0159

Andrea Campos Herrera, Francisco Valenzuela Zamudio, M. R. Segura Campos

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Abstract

Amaranth is a pseudocereal rich in macronutrients and micronutrients, with about 60 species cultivated worldwide. It is a high nutritional value food because of its many essential amino acids. Recent investigations demonstrate that the phytochemicals and extracts of amaranth have beneficial effects on health, including antidiabetic potential, a decrease in plasmatic cholesterol and blood pressure, and protection from oxidative stress and inflammation. Nowadays, type 2 diabetes has increased worldwide, becoming a problem of public health that makes it necessary to look for alternative strategies for its prevention and treatment. This review aims to summarize the antidiabetic potential of diverse species of the Amaranth genus. A bibliographical review was updated on the plant's therapeutic potential, including stem, leaves, and seeds, to know the benefits and potential as an adjuvant in treating and managing diabetes and associated pathologies (hypertension, dyslipidemia, and heart disease). This analysis contributes to the generation of knowledge about the therapeutic effects of amaranth, promoting the creation of new products, and the opportunity to conduct clinical trials to assess their safety and efficacy.

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苋菜的治疗作用：植物的抗糖尿病潜力分析。

苋菜是一种富含宏量营养素和微量营养素的伪谷物，全世界约有 60 个种植品种。苋菜含有多种人体必需的氨基酸，是一种营养价值很高的食物。最近的研究表明，苋菜的植物化学物质和提取物对健康有益，包括抗糖尿病潜力、降低血浆胆固醇和血压，以及防止氧化应激和炎症。如今，2 型糖尿病在全球呈上升趋势，已成为一个公共卫生问题，因此有必要寻找预防和治疗该病的替代策略。本综述旨在总结苋属不同物种的抗糖尿病潜力。我们更新了有关苋属植物（包括茎、叶和种子）治疗潜力的文献综述，以了解其作为辅助剂治疗和控制糖尿病及相关病症（高血压、血脂异常和心脏病）的益处和潜力。这项分析有助于了解苋菜的治疗效果，促进新产品的开发，并有机会进行临床试验，以评估其安全性和有效性。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.