Anal and perianal disorders

Bruce D. George, Jonathan Gosling
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Abstract

Most anal diseases can be diagnosed by a careful history and examination. Management of haemorrhoids involves exclusion of more serious pathology, adequate explanation of the disorder, and dietary and defecatory advice; most do not require additional treatment. Outpatient procedures or surgical intervention can be required for more symptomatic cases. Anal fissures are initially managed with bulking laxatives and non-constipating analgesics; glyceryl trinitrate ointment is standard first-line treatment. Lateral internal sphincterotomy is indicated rarely for fissures that do not heal after pharmacological management, although it is associated with a small risk of impaired continence. Anal fistulae and abscesses represent extremes of a single disease spectrum. Perianal abscesses should be treated by prompt adequate surgical drainage. Low fistulae are treated by fistulotomy. High fistulae require more complex sphincter-preserving techniques. Patients with faecal incontinence should be investigated with anal physiological tests and endoanal ultrasonography. Conservative treatment includes dietary modification, constipating drugs, physiotherapy and biofeedback. Sacral nerve stimulation represents a new, expensive but relatively non-invasive treatment option for patients with faecal incontinence after failure of first-line conservative therapy. Patients with functional constipation should be assessed to distinguish slow transit from obstructed defecation. Laparoscopic ventral rectopexy can be appropriate for selected patients with rectal intussusception.

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肛门和肛周疾病
大多数肛门疾病都可以通过仔细询问病史和检查来确诊。痔疮的治疗包括排除更严重的病变、充分解释病症、提供饮食和排便建议;大多数痔疮不需要额外的治疗。症状较重的病例可能需要门诊治疗或手术干预。肛裂初期可使用膨胀性泻药和非便秘性止痛药;三硝酸甘油酯软膏是标准的一线治疗方法。外侧内括约肌切开术很少用于药物治疗后仍未愈合的肛裂,但这种治疗方法会有轻微的排便障碍风险。肛瘘和脓肿是同一疾病谱的两个极端。肛周脓肿应及时进行适当的手术引流。低位瘘管可通过瘘管切开术治疗。高位瘘管需要更复杂的括约肌保留技术。大便失禁患者应接受肛门生理检查和肛内超声波检查。保守治疗包括饮食调节、便秘药物、物理治疗和生物反馈。骶神经刺激疗法是一种新的、昂贵但相对非侵入性的治疗方法,适用于一线保守治疗失败后的大便失禁患者。应对功能性便秘患者进行评估,以区分排便缓慢和排便受阻。腹腔镜腹侧直肠切除术适用于特定的直肠肠套叠患者。
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Contents Editorial Board Editorial: Medical problems in pregnancy Management of pre-gestational diabetes in pregnancy Endocrine disorders in pregnancy
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