The golden hour in shock management: do a lot, do it quickly

IF 17.7 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-04-01 DOI:10.1093/eurheartjsupp/suae023
Marco Marini, S. Belleggia, Leonardo Brugiatelli, Matteo Francioni, I. Battistoni, M. Shkoza, G. Pongetti, L. Angelini, L. Belfioretti, M. Matassini
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Abstract

Cardiogenic shock can be defined as a state of inadequate organ perfusion linked primarily to cardiac pump dysfunction. The two predominant causes of this condition are acute myocardial infarction and acutely decompensated heart failure (ADHF). In recent years, a significant increase in cases of cardiogenic shock from ADHF has been described. Recent evidence has defined that the factors with the greatest impact on the prognosis in this context are the early clinical assessment, the definition of the aetiology, the timely application of pharmacological therapies, or individualized mechanical supports for the circulation. Haemodynamic monitoring can help in the phenotyping of cardiogenic shock and therefore guide therapeutic choices, especially if implemented with the aid of advanced monitoring tools such as the Swan–Ganz catheter. Finally, the presence of a dedicated shock team in the ‘hub’ centres is fundamental, which facilitates the choice of the best therapeutic strategy on a case-by-case basis.
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冲击管理的黄金时间:多做、快做
心源性休克可定义为主要与心泵功能障碍有关的器官灌注不足状态。造成这种情况的两个主要原因是急性心肌梗死和急性失代偿性心力衰竭(ADHF)。近年来,ADHF 引起的心源性休克病例明显增多。最近的证据表明,在这种情况下,对预后影响最大的因素是早期临床评估、病因定义、及时应用药物治疗或个性化的循环机械支持。血流动力学监测可以帮助确定心源性休克的表型,从而指导治疗方案的选择,尤其是在使用 Swan-Ganz 导管等先进监测工具的情况下。最后,在 "枢纽 "中心设立专门的休克小组至关重要,这有助于根据具体情况选择最佳治疗策略。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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