Comparative Analysis of Angiographic Parameters and Percutaneous Coronary Intervention Outcomes in Diverse Populations in Türkiye.

Mehmet Rasih Sonsöz, İlyas Çetin, Cemal Ozanalp, Şevval Kılıç, Göksenin Cansu Özdoğan, Gamze Acar, Gamze Gençol Akçay, Yelda Saltan Özateş, Y. Güler, Ahmet Güler
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Abstract

OBJECTIVE Due to the conflict in Syria since 2011, more than 3.5 million Syrian citizens reside in Türkiye. Because Syrian patients were underrepresented in previous studies on percutaneous coronary intervention (PCI) outcomes, we aimed to analyze the severity of coronary artery disease and in-hospital outcomes of PCI in this population. METHODS We retrospectively analyzed 142 Syrian patients who underwent PCI at our center between June 2020 and October 2022 and compared the data with that of age- and sex-matched Turkish patients (n = 271) who also underwent PCI. We assessed comorbidities, coronary anatomy features, procedural complications, and in-hospital cardiovascular outcomes (Major Adverse Cardiac and Cerebrovascular Events, MACCE). RESULTS The mean age of the study population was 57 ± 12 years, with 15% being female. Clinical indication and coronary anatomy features did not differ between the groups. However, the Synergy between Percutaneous Coronary Intervention with Taxus and Cardiac Surgery (SYNTAX) score was higher in Syrian patients compared to Turkish patients (16 [11-22] vs. 12 [8-20]; P < 0.001). Complex PCI rates, in-hospital bleeding and contrast nephropathy were similar in both groups. MACCE was comparable between Syrian and Turkish patients (13 [4.8%] vs. 13 [9.2%], P = 0.083). CONCLUSION Comparable MACCE rates were observed in both ethnic groups undergoing PCI, despite a higher SYNTAX score in Syrian patients. Future research should investigate whether similar in-hospital MACCE rates are observed in other regions of Türkiye and whether long-term cardiovascular outcomes differ between Turkish and Syrian patients.
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图尔基耶不同人群血管造影参数和经皮冠状动脉介入治疗结果的比较分析。
目的:由于 2011 年以来的叙利亚冲突,350 多万叙利亚公民居住在土耳其。方法 我们回顾性分析了 2020 年 6 月至 2022 年 10 月期间在本中心接受 PCI 治疗的 142 名叙利亚患者,并与同样接受 PCI 治疗的年龄和性别匹配的土耳其患者(n = 271)的数据进行了比较。我们评估了合并症、冠状动脉解剖特征、手术并发症和院内心血管预后(主要不良心脑血管事件,MACCE)。结果研究对象的平均年龄为 57 ± 12 岁,其中女性占 15%。两组的临床指征和冠状动脉解剖特征无差异。然而,与土耳其患者相比,叙利亚患者的经皮冠状动脉介入治疗与Taxus和心脏手术之间的协同作用(SYNTAX)评分更高(16 [11-22] vs. 12 [8-20]; P < 0.001)。两组患者的复杂 PCI 发生率、院内出血和造影剂肾病发生率相似。结论尽管叙利亚患者的SYNTAX评分更高,但在接受PCI治疗的两个种族群体中均观察到了相似的MACCE率。未来的研究应调查土耳其其他地区是否也观察到类似的院内MACCE率,以及土耳其和叙利亚患者的长期心血管预后是否存在差异。
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