A Review of the Medicinal Value and Chemical Composition of Flavonoids from Pongamia Pinnata: Recent Work in Drug Advancement and Therapeutics

IF 0.3 Q4 PHARMACOLOGY & PHARMACY Current Drug Therapy Pub Date : 2024-04-01 DOI:10.2174/0115748855288101240320061757
Trilochan Satapathy, Yogesh Kumar, R. K. Pandey, S. Shukla, Shiv Kumar Bhardwaj, Beena Gidwani
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引用次数: 0

Abstract

Traditional medicine in many countries, including those where Pongamia pinnata (L.) Pierreis grown, uses the plant for a wide variety of purposes, including the treatment of piles, skin problems, and wounds. The objective of the present study was to discuss the medicinal value and chemical composition of flavonoids obtained from P. pinnata. All parts of the plant contain several phytoconstituents responsible for biological activity. These compounds include numerous types of flavonoid derivatives, such as flavones and flavans, as well as terpenes, steroids, and fatty acids. The information required about the plant and advancement in therapeutics was gathered from Pubmed, ScienceDirect and Cochrane Library. Many different types of biological activity, including antioxidant, antibacterial, anti-inflammatory, and anti-diabetic properties, have been observed in plant products from this species in pharmacological research. However, more research into the plant's phytochemical profile and the complicated pharmacological effects is required. This is because our current understanding of the plant's chemical ingredients and the methods by which they exhibit certain biological activities is limited. Thus, information regarding active constituents is required to develop novel therapeutics and additional research on the toxicity of the other chemicals identified from this plant is necessary.
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凤仙花黄酮类化合物的药用价值和化学成分综述:药物开发和治疗方面的最新研究成果
在许多国家,包括种植 Pongamia pinnata (L.)Pierre 的国家,传统医学将这种植物用于多种用途,包括治疗痔疮、皮肤问题和伤口。本研究的目的是讨论从羽扇豆中提取的黄酮类化合物的药用价值和化学成分。该植物的所有部分都含有多种具有生物活性的植物成分。这些化合物包括多种类型的类黄酮衍生物,如黄酮和黄烷,以及萜烯、类固醇和脂肪酸。我们从 Pubmed、ScienceDirect 和 Cochrane 图书馆收集了有关该植物和治疗学发展所需的信息。在药理学研究中,已观察到该物种的植物产品具有许多不同类型的生物活性,包括抗氧化、抗菌、抗炎和抗糖尿病特性。然而,还需要对该植物的植物化学成分及其复杂的药理作用进行更多的研究。这是因为我们目前对该植物的化学成分及其发挥某些生物活性的方法的了解还很有限。因此,需要有关活性成分的信息来开发新的治疗方法,同时还需要对从该植物中发现的其他化学物质的毒性进行更多的研究。
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来源期刊
Current Drug Therapy
Current Drug Therapy PHARMACOLOGY & PHARMACY-
CiteScore
1.30
自引率
0.00%
发文量
50
期刊介绍: Current Drug Therapy publishes frontier reviews of high quality on all the latest advances in drug therapy covering: new and existing drugs, therapies and medical devices. The journal is essential reading for all researchers and clinicians involved in drug therapy.
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