Role of Coriolis flow measurement technology in validation of model of syringe driver performance

IPEM-translation Pub Date : 2024-04-12 DOI:10.1016/j.ipemt.2024.100027

D.M. Clarkson , M. Tshangini

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Abstract

The development of a flow/pressure measurement system in association with Bronkhorst High-Tech B.V. incorporating a Coriolis flow transducer, provided an opportunity to observe the flow/pressure dynamics of syringe drivers. A model of flow/pressure performance of syringe drivers was established where key variable factors included the compliance of the connected system and the associated line resistance. It was identified that the flow/pressure dynamics observed with the flow measurement system incorporating the Coriolis transducer matched that of the model. In this consideration the dominant compliance contribution related to that of the syringe. The model operates by considering the notional volume change in the residual fluid volume in the syringe with inflow from stepper motor action and outflow in the interval between sequential pulses. While many of the observations in the literature of syringe driver function are qualitative, the model allows a more precise prediction of associated device performance.

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科里奥利流量测量技术在验证注射器驱动器性能模型中的作用

与布琅轲锶特高科技公司合作开发的流量/压力测量系统采用了科里奥利流量传感器，为观察注射器驱动器的流量/压力动态提供了机会。建立了注射器驱动器的流量/压力性能模型，其中关键的可变因素包括连接系统的顺应性和相关的线路电阻。结果表明，使用科里奥利传感器的流量测量系统观察到的流量/压力动态与模型相符。在这种情况下，主要的顺应性与注射器的顺应性有关。该模型的运行考虑了注射器中残留流体体积的名义体积变化，步进电机作用产生流入，连续脉冲之间的间隔产生流出。虽然文献中对注射器驱动器功能的许多观察都是定性的，但该模型可以更精确地预测相关设备的性能。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

IPEM-translation Medicine and Dentistry (General)

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63 days