Quality of life, psychological states, and personality traits in patients with pectus excavatum

Kohei Matsuda MD , Daisuke Fujisawa MD , Kyohei Masai MD , Naoki Miyazaki , Shigeki Suzuki MD , Yu Okubo MD , Kaoru Kaseda MD , Keisuke Asakura MD , Tomoyuki Hishida MD , Hisao Asamura MD
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Abstract

Objective

The quality of life (QOL) and psychological states of patients with pectus excavatum (PE) have yet to be well understood. This study aimed to evaluate the health-related QOL (HRQOL), psychological states, and personality traits of patients with PE, alongside the associations of these factors with the severity of PE.

Methods

A cross-sectional evaluation was prospectively performed in patients scheduled to undergo PE repair surgery between July 2019 and April 2021. The primary outcome was the patients’ HRQOL, and the secondary outcomes were depression, social anxiety, self-efficacy, and personality traits.

Results

In total, 129 patients were subjected to analyses. Patients' HRQOL had a lower role component summary score (mean ± standard deviation: 41.8 ± 12.8, P < .001) than the general population controls. Patients' HRQOL had a significantly better physical component summary (54.0 ± 10.4, P < .001) and mental component summary (53.3 ± 8.8, P < .001) than that of the general population. Fourteen patients' (10.9%) and 56 patients' (43.4%) scores indicated the presence of depression and social anxiety disorder, respectively. Patients’ self-efficacy (46.1 ± 11.4, P, .001) and level of extraversion (46.5 ± 11.8, P < .001) were lower than those of the general population. No significant correlation was found between the severity of PE and these scores.

Conclusions

Our study revealed that patients with PE had decreased social-role QOL, depressive tendencies, increased social anxiety, lower self-efficacy, and introversion. No correlation between the severity of PE and the patients’ psychological outcomes leads us to conclude that surgical implications of PE should not be decided solely by a physical index.

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乳突患者的生活质量、心理状态和个性特征
目的:人们尚未充分了解乳房下垂(PE)患者的生活质量(QOL)和心理状态。本研究旨在评估PE患者的健康相关QOL(HRQOL)、心理状态和人格特质,以及这些因素与PE严重程度的关系。方法对2019年7月至2021年4月期间计划接受PE修复手术的患者进行前瞻性横断面评估。主要结果是患者的 HRQOL,次要结果是抑郁、社交焦虑、自我效能感和人格特质。与普通对照组相比,患者的 HRQOL 的角色成分总分较低(平均值 ± 标准差:41.8 ± 12.8,P < .001)。与普通人群相比,患者的 HRQOL 的身体部分总分(54.0 ± 10.4,P < .001)和精神部分总分(53.3 ± 8.8,P < .001)明显更高。14名患者(10.9%)和56名患者(43.4%)的得分分别表明他们患有抑郁症和社交焦虑症。患者的自我效能感(46.1 ± 11.4,P,.001)和外向程度(46.5 ± 11.8,P < .001)均低于普通人群。结论我们的研究显示,PE 患者的社会角色 QOL 下降、抑郁倾向、社交焦虑增加、自我效能感降低、性格内向。PE 的严重程度与患者的心理结果之间没有相关性,因此我们得出结论,PE 的手术影响不应仅由生理指标来决定。
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