The case for a ketogenic diet in the management of kidney disease

IF 3.7 2区 医学 Q2 ENDOCRINOLOGY & METABOLISM BMJ Open Diabetes Research & Care Pub Date : 2024-04-01 DOI:10.1136/bmjdrc-2024-004101
Shaminie J Athinarayanan, Caroline G P Roberts, Chandan Vangala, Greeshma K Shetty, Amy L McKenzie, Thomas Weimbs, Jeff S Volek
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Abstract

Ketogenic diets have been widely used for weight loss and are increasingly used in the management of type 2 diabetes. Despite evidence that ketones have multiple positive effects on kidney function, common misconceptions about ketogenic diets, such as high protein content and acid load, have prevented their widespread use in individuals with impaired kidney function. Clinical trial evidence focusing on major adverse kidney events is sparse. The aim of this review is to explore the effects of a ketogenic diet, with an emphasis on the pleiotropic actions of ketones, on kidney health. Given the minimal concerns in relation to the potential renoprotective effects of a ketogenic diet, future studies should evaluate the safety and efficacy of ketogenic interventions in kidney disease. No data are available.
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生酮饮食治疗肾病的理由
生酮饮食已被广泛用于减肥,并越来越多地用于 2 型糖尿病的治疗。尽管有证据表明酮体对肾功能有多种积极影响,但对生酮饮食的常见误解,如高蛋白含量和酸负荷,阻碍了生酮饮食在肾功能受损者中的广泛应用。关注主要肾脏不良事件的临床试验证据并不多。本综述旨在探讨生酮饮食对肾脏健康的影响,重点是酮的多效应。鉴于对生酮饮食潜在肾保护作用的关注极少,未来的研究应评估生酮干预对肾脏疾病的安全性和有效性。暂无数据。
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来源期刊
BMJ Open Diabetes Research & Care
BMJ Open Diabetes Research & Care Medicine-Endocrinology, Diabetes and Metabolism
CiteScore
9.30
自引率
2.40%
发文量
123
审稿时长
18 weeks
期刊介绍: BMJ Open Diabetes Research & Care is an open access journal committed to publishing high-quality, basic and clinical research articles regarding type 1 and type 2 diabetes, and associated complications. Only original content will be accepted, and submissions are subject to rigorous peer review to ensure the publication of high-quality — and evidence-based — original research articles.
期刊最新文献
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