Enhanced Laplace approximation

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-04-26 DOI:10.1016/j.jmva.2024.105321
Jeongseop Han, Youngjo Lee
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Abstract

The Laplace approximation has been proposed as a method for approximating the marginal likelihood of statistical models with latent variables. However, the approximate maximum likelihood estimators derived from the Laplace approximation are often biased for binary or temporally and/or spatially correlated data. Additionally, the corresponding Hessian matrix tends to underestimates the standard errors of these approximate maximum likelihood estimators. While higher-order approximations have been suggested, they are not applicable to complex models, such as correlated random effects models, and fail to provide consistent variance estimators. In this paper, we propose an enhanced Laplace approximation that provides the true maximum likelihood estimator and its consistent variance estimator. We study its relationship with the variational Bayes method. We also define a new restricted maximum likelihood estimator for estimating dispersion parameters and study their asymptotic properties. Enhanced Laplace approximation generally demonstrates how to obtain the true restricted maximum likelihood estimators and their variance estimators. Our numerical studies indicate that the enhanced Laplace approximation provides a satisfactory maximum likelihood estimator and restricted maximum likelihood estimator, as well as their variance estimators in the frequentist perspective. The maximum likelihood estimator and restricted maximum likelihood estimator can be also interpreted as the posterior mode and marginal posterior mode under flat priors, respectively. Furthermore, we present some comparisons with Bayesian procedures under different priors.

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增强拉普拉斯近似
拉普拉斯近似法是一种用于近似潜在变量统计模型边际似然的方法。然而,对于二元数据或时间和/或空间相关数据,从拉普拉斯近似法得出的近似极大似然估计值往往存在偏差。此外,相应的 Hessian 矩阵往往会低估这些近似极大似然估计值的标准误差。虽然有人提出了更高阶的近似值,但它们不适用于复杂的模型,如相关随机效应模型,也不能提供一致的方差估计值。在本文中,我们提出了一种增强的拉普拉斯近似方法,它能提供真正的最大似然估计值及其一致的方差估计值。我们研究了它与变异贝叶斯方法的关系。我们还定义了用于估计离散参数的新的受限最大似然估计器,并研究了其渐近特性。增强拉普拉斯近似一般展示了如何获得真正的受限极大似然估计器及其方差估计器。我们的数值研究表明,增强拉普拉斯近似提供了一个令人满意的最大似然估计器和受限最大似然估计器,以及频繁主义视角下的它们的方差估计器。最大似然估计和受限最大似然估计也可以分别解释为平面先验下的后验模式和边际后验模式。此外,我们还对不同先验下的贝叶斯程序进行了比较。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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