{"title":"Enhanced Laplace approximation","authors":"Jeongseop Han, Youngjo Lee","doi":"10.1016/j.jmva.2024.105321","DOIUrl":null,"url":null,"abstract":"<div><p>The Laplace approximation has been proposed as a method for approximating the marginal likelihood of statistical models with latent variables. However, the approximate maximum likelihood estimators derived from the Laplace approximation are often biased for binary or temporally and/or spatially correlated data. Additionally, the corresponding Hessian matrix tends to underestimates the standard errors of these approximate maximum likelihood estimators. While higher-order approximations have been suggested, they are not applicable to complex models, such as correlated random effects models, and fail to provide consistent variance estimators. In this paper, we propose an enhanced Laplace approximation that provides the true maximum likelihood estimator and its consistent variance estimator. We study its relationship with the variational Bayes method. We also define a new restricted maximum likelihood estimator for estimating dispersion parameters and study their asymptotic properties. Enhanced Laplace approximation generally demonstrates how to obtain the true restricted maximum likelihood estimators and their variance estimators. Our numerical studies indicate that the enhanced Laplace approximation provides a satisfactory maximum likelihood estimator and restricted maximum likelihood estimator, as well as their variance estimators in the frequentist perspective. The maximum likelihood estimator and restricted maximum likelihood estimator can be also interpreted as the posterior mode and marginal posterior mode under flat priors, respectively. Furthermore, we present some comparisons with Bayesian procedures under different priors.</p></div>","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":null,"pages":null},"PeriodicalIF":16.4000,"publicationDate":"2024-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Accounts of Chemical Research","FirstCategoryId":"100","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0047259X24000289","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
The Laplace approximation has been proposed as a method for approximating the marginal likelihood of statistical models with latent variables. However, the approximate maximum likelihood estimators derived from the Laplace approximation are often biased for binary or temporally and/or spatially correlated data. Additionally, the corresponding Hessian matrix tends to underestimates the standard errors of these approximate maximum likelihood estimators. While higher-order approximations have been suggested, they are not applicable to complex models, such as correlated random effects models, and fail to provide consistent variance estimators. In this paper, we propose an enhanced Laplace approximation that provides the true maximum likelihood estimator and its consistent variance estimator. We study its relationship with the variational Bayes method. We also define a new restricted maximum likelihood estimator for estimating dispersion parameters and study their asymptotic properties. Enhanced Laplace approximation generally demonstrates how to obtain the true restricted maximum likelihood estimators and their variance estimators. Our numerical studies indicate that the enhanced Laplace approximation provides a satisfactory maximum likelihood estimator and restricted maximum likelihood estimator, as well as their variance estimators in the frequentist perspective. The maximum likelihood estimator and restricted maximum likelihood estimator can be also interpreted as the posterior mode and marginal posterior mode under flat priors, respectively. Furthermore, we present some comparisons with Bayesian procedures under different priors.
期刊介绍:
Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance.
Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.