Improving therapeutic outcomes in heart failure with reduced nonvalvular ejection fraction: A clinical study of heart failure education intervention

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2024-04-29 DOI:10.1002/clc.24265

Xueli Tian MM, Xiaozeng Li MM, Qingqing Zhang, Xiangling Qiao, Xin Li MM, Zijian Zhang

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Abstract

Objective

The current study delves into the impact of heart failure education intervention on improving therapeutic outcomes for heart failure (HF) patients with reduced nonvalvular ejection fraction.

Methods

There involved a total of 60 HF patients with non-valvular ejection fraction reduction who met the inclusion requirements. Patients enrolled were randomly distributed into an observation group and a control group. The observation group received heart failure education intervention, while the control group received conventional intervention. The therapeutic effect, changes in physical indicators, cardiac function indicators, coagulation function, self-management scale scores, and the incidence of adverse cardiovascular events were meticulously evaluated.

Results

The total effective proportion in the observation group was 96.67%, which was significantly higher than the control group's proportion of 76.67% (p < .05). After treatment, several parameters in the observation group showed significant improvements compared to the control group: hs-CRP, IL-6, LVEDV value, LVESV value, PT value, APTT value, and TT value were all evidently lower in the observation group. Additionally, the cardiac index, LVEF value, and heart failure self-management scale fraction were significantly higher in the observation group compared to the control group (p < .05). Furthermore, the incidence of adverse cardiovascular events in the observation group was only 6.67%, which was significantly lower than the control group's incidence of 20.00% (p < .05).

Conclusion

Heart failure education intervention demonstrates effectiveness in improving the therapeutic outcomes for HF patients and reduced nonvalvular ejection fraction. Additionally, it enhances patients' self-management abilities. Given these positive results, it is highly recommended to promote and implement HF education intervention in clinical practice.

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改善非瓣膜性射血分数降低型心力衰竭的治疗效果：心力衰竭教育干预临床研究

目的本研究探讨心力衰竭教育干预对改善非瓣膜性射血分数降低的心力衰竭（HF）患者治疗效果的影响。方法共有 60 名符合纳入要求的非瓣膜射血分数降低的心衰患者参与研究。入组患者被随机分为观察组和对照组。观察组接受心衰教育干预，对照组接受常规干预。对治疗效果、身体指标变化、心脏功能指标、凝血功能、自我管理量表评分以及心血管不良事件发生率进行细致评估。结果观察组总有效率为 96.67%，明显高于对照组的 76.67%（P < .05）。治疗后，观察组的多项指标均较对照组有明显改善：观察组的 hs-CRP、IL-6、LVEDV 值、LVESV 值、PT 值、APTT 值、TT 值均明显降低。此外，与对照组相比，观察组的心脏指数、LVEF 值和心衰自我管理量表评分均明显高于对照组（P < .05）。此外，观察组心血管不良事件的发生率仅为 6.67%，明显低于对照组的 20.00%（p <.05）。结论心衰教育干预能有效改善心衰患者的治疗效果，降低非瓣膜性射血分数。此外，它还能提高患者的自我管理能力。鉴于这些积极的结果，强烈建议在临床实践中推广和实施心力衰竭教育干预。

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