Benign prostatic hyperplasia during active surveillance for prostate cancer: is it time to define management strategies?

IF 5.8 2区 医学 Q1 ONCOLOGY Prostate Cancer and Prostatic Diseases Pub Date : 2024-04-29 DOI:10.1038/s41391-024-00837-9
Eugenio Bologna, Leslie Claire Licari, Francesco Ditonno, Rocco Simone Flammia, Aldo Brassetti, Costantino Leonardo, Antonio Franco, Cosimo De Nunzio, Riccardo Autorino
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前列腺癌主动监测期间的良性前列腺增生:现在是确定管理策略的时候了吗?
近年来,决定前列腺癌(PCa)患者是否有资格接受主动监测(AS)的标准发生了很大变化。对疾病分期、PSA 值、活检核心受累情况、格里森评分(GS)和综合风险评分分类等因素进行了重新评估[1, 2],以扩大适合接受主动监测的患者群体。尽管适用范围扩大了,但在美国仍有超过 40% 的低风险患者立即接受了治疗,导致更多患者接受了不必要的治疗[3]。从历史上看,在美国实施 AS 的主要是学术机构,社区泌尿科采用率较低。然而,最近的趋势表明,在更广泛的医疗机构中,AS 的使用率大幅快速上升,导致美国确诊 PCa 患者的主动监测率显著上升[4, 5]。有趣的是,更宽泛的资格标准不仅导致更多患者选择 AS,还延长了个人对这一管理策略的承诺期。这种模式的转变导致了有症状的良性前列腺增生症(BPH)在 AS 患者中的发病率上升,这种疾病通常在 40 岁左右出现,之后逐渐变得更加常见[6]。目前,对于在强直性脊柱炎期间因良性前列腺增生继发中度至重度尿失禁而需要手术治疗的患者的管理、首选的手术干预方式以及对后续 PCa 治疗的潜在影响,尚无具体建议。
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来源期刊
Prostate Cancer and Prostatic Diseases
Prostate Cancer and Prostatic Diseases 医学-泌尿学与肾脏学
CiteScore
10.00
自引率
6.20%
发文量
142
审稿时长
6-12 weeks
期刊介绍: Prostate Cancer and Prostatic Diseases covers all aspects of prostatic diseases, in particular prostate cancer, the subject of intensive basic and clinical research world-wide. The journal also reports on exciting new developments being made in diagnosis, surgery, radiotherapy, drug discovery and medical management. Prostate Cancer and Prostatic Diseases is of interest to surgeons, oncologists and clinicians treating patients and to those involved in research into diseases of the prostate. The journal covers the three main areas - prostate cancer, male LUTS and prostatitis. Prostate Cancer and Prostatic Diseases publishes original research articles, reviews, topical comment and critical appraisals of scientific meetings and the latest books. The journal also contains a calendar of forthcoming scientific meetings. The Editors and a distinguished Editorial Board ensure that submitted articles receive fast and efficient attention and are refereed to the highest possible scientific standard. A fast track system is available for topical articles of particular significance.
期刊最新文献
Lipidomic profiling in metastatic prostate cancer captures tumor metabolic rewiring and its modulation by androgen receptor-targeting therapy. Natural history of untreated prostate cancer: a comprehensive review of long-term progression patterns and survival outcomes. Perioperative outcomes of ongoing antithrombotic therapy during endoscopic surgery for benign prostatic hyperplasia: a systematic review and meta-analysis of observational studies. The impact of minimally invasive surgical therapy for Benign prostatic hyperplasia on sexual function: a systematic review and meta-analysis. Robot-assisted MRI/US transperineal target prostate biopsy with Biobot Mona Lisa 2.0: first experience in Europe.
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