Episodic Presentations of Pustular Pyoderma Gangrenosum in PLHIV: A Case Report and Brief Review of Literature

IF 1 4区 医学 Q4 DERMATOLOGY Indian Journal of Dermatology Pub Date : 2024-04-29 DOI:10.4103/ijd.ijd_680_23
Vijayashree Gokhale, Ponvijaya M. Yadav, Mahabir P. Mishra, Giduturi Naga Lakshmi Vineetha
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Abstract

We report a case of a 54-year-old female diagnosed with HIV and antiretroviral therapy (ART) for the same. Seven years ago, she suffered from fever, cough and weight loss, was diagnosed with pulmonary tuberculosis and also seropositive for HIV. She suffered from Herpes Zoster infection, after which her ART regimen was changed to TLD (tenofovir, lamivudine and dolutegravir). The patient presented with two episodes of pyoderma gangrenosum (PG), which were biopsy-proven, corresponding to a rise in CD4 counts above 500. She responded to glucocorticoids, both systemic and topical.

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脓疱性脓疱病在艾滋病毒感染者中的发作性表现:病例报告和文献简评
我们报告了一例 54 岁女性的病例,她被诊断出感染了艾滋病毒,并接受了抗逆转录病毒疗法(ART)治疗。七年前,她发烧、咳嗽、体重减轻,被诊断为肺结核,HIV 血清也呈阳性。带状疱疹感染后,她的抗逆转录病毒疗法改为 TLD(替诺福韦、拉米夫定和多罗替拉韦)。患者出现了两次脓皮病(PG),经活检证实,CD4 细胞计数上升到 500 以上。她对全身和局部使用糖皮质激素均有反应。
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来源期刊
Indian Journal of Dermatology
Indian Journal of Dermatology Medicine-Dermatology
CiteScore
1.80
自引率
0.00%
发文量
217
审稿时长
47 weeks
期刊介绍: The journal publishes information related to skin-pathology and different modes of therapeutics, including dermatosurgery and cosmetic dermatology. Likewise, it carries articles on leprosy, STI and HIV/AIDS. The editorial board encourages the authors to publish articles addressing emerging techniques and developments in the subject specialty, in the form of Original investigations, Narrative and Systematic Reviews as well as Case Reports. The journal aims at publishing Editorials and Commentaries from eminent personalities on a regular basis.
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