Discovering the Potential Value of Coenzyme Q10 as an Adjuvant Treatment in Patients With Depression.

IF 2.9 3区 医学 Q2 PHARMACOLOGY & PHARMACY Journal of Clinical Psychopharmacology Pub Date : 2024-04-29 DOI:10.1097/jcp.0000000000001845
Mahnam Majmasanaye, Maryam Mehrpooya, Hasan Amiri, Azadeh Eshraghi
{"title":"Discovering the Potential Value of Coenzyme Q10 as an Adjuvant Treatment in Patients With Depression.","authors":"Mahnam Majmasanaye, Maryam Mehrpooya, Hasan Amiri, Azadeh Eshraghi","doi":"10.1097/jcp.0000000000001845","DOIUrl":null,"url":null,"abstract":"Depressive disorder or mental cold is the most common mental disorder, and depression exists all over the world and in all countries and cultures. The results of several studies have shown that using compounds with antioxidant properties has been fruitful in patients with depression. Coenzyme Q10 (CoQ10) is a fat-soluble antioxidant and exerts its antioxidant effect by directly neutralizing free radicals or reducing tocopherol and preventing the inhibition of mitochondrial activity because of oxidative stress. This study aimed to investigate the effects of oral CoQ10 in patients with depression as an adjunctive treatment.","PeriodicalId":15455,"journal":{"name":"Journal of Clinical Psychopharmacology","volume":"22 1","pages":""},"PeriodicalIF":2.9000,"publicationDate":"2024-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Clinical Psychopharmacology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/jcp.0000000000001845","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}
引用次数: 0

Abstract

Depressive disorder or mental cold is the most common mental disorder, and depression exists all over the world and in all countries and cultures. The results of several studies have shown that using compounds with antioxidant properties has been fruitful in patients with depression. Coenzyme Q10 (CoQ10) is a fat-soluble antioxidant and exerts its antioxidant effect by directly neutralizing free radicals or reducing tocopherol and preventing the inhibition of mitochondrial activity because of oxidative stress. This study aimed to investigate the effects of oral CoQ10 in patients with depression as an adjunctive treatment.
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
发现辅酶Q10作为抑郁症患者辅助治疗的潜在价值。
抑郁症或精神冷漠是最常见的精神疾病,抑郁症存在于世界各地、所有国家和文化中。多项研究结果表明,使用具有抗氧化特性的化合物对抑郁症患者有疗效。辅酶 Q10(CoQ10)是一种脂溶性抗氧化剂,通过直接中和自由基或还原生育酚,防止氧化应激对线粒体活性的抑制,从而发挥抗氧化作用。本研究旨在探讨口服辅酶Q10对抑郁症患者的辅助治疗效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
CiteScore
4.00
自引率
3.40%
发文量
231
审稿时长
4-8 weeks
期刊介绍: Journal of Clinical Psychopharmacology, a leading publication in psychopharmacology, offers a wide range of articles reporting on clinical trials and studies, side effects, drug interactions, overdose management, pharmacogenetics, pharmacokinetics, and psychiatric effects of non-psychiatric drugs. The journal keeps clinician-scientists and trainees up-to-date on the latest clinical developments in psychopharmacologic agents, presenting the extensive coverage needed to keep up with every development in this fast-growing field.
期刊最新文献
Recurrent Pancreatitis Associated With Atomoxetine Use in a 9-Year-Old Boy: A Case Report. Ethics in Psychedelic Science: Promises and Responsibilities. Ischemic Priapism With Therapeutic Serum Concentrations of Psychotropic Medications. The Treatment of Iatrogenic Anorgasmia in a Male Patient on Clozapine for Treatment-Resistant Schizophrenia: The Role of Pseudoephedrine. Myocarditis on Clozapine 50 mg/d in a Patient With Parkinson's Disease.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1