Assessment of stereotactic high-resolution detectors for stereotactic body radiotherapy: comparative analysis between myQA® SRS and Gafchromic EBT-XD films

IF 1.5 4区 环境科学与生态学 Q3 BIOLOGY Radiation and Environmental Biophysics Pub Date : 2024-04-29 DOI:10.1007/s00411-024-01071-6
Dinesan Chinnaiya, Gopinath Mudhana
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Abstract

The study aimed to evaluate dosimetry systems used for stereotactic body radiotherapy (SBRT), specifically 2D array dosimetry and film dosimetry systems, for exploring their characteristics and clinical suitability. For this, high-resolution myQA SRS detectors and Gafchromic EBT-XD films were employed. Film analysis included net optical density (OD) values depending on energy, dose rate, scanner orientation, scanning side, and post-exposure growth. For myQA SRS, signal values were evaluated in terms of dose rate (400–1400 MU/min) and angular dependence (0–180° at 30° intervals) along with couch angles of 0°, 45°, and 90°. Pre-treatment verification included 32 SBRT patients for whom myQA SRS results were compared with those obtained with Gafchromic EBT-XD films. Analysis revealed less than 1% deviation in net OD for energy and dose rate dependence. Scanner orientation caused 2.5% net OD variation, with minimal differences between film front and back scan orientations (variance < 1.0%). A rapid OD rise occurred within six hours post-exposure, followed by gradual increase. The myQA SRS detector showed − 3.7% dose rate dependence (400 MU/min), while the angular dependence at 90° was − 26.7%. A correction factor effectively reduced these differences to < 1%. For myQA SRS, gamma passing rates were—93.6% (2%/1 mm), while those for EBT-XD films were—92.8%. Improved rates were observed with 3%/1 mm: for myQA SRS—97.9%, and for EBT-XD film—98.16%. In contrast, for 2%/2 mm with 10% threshold, for myQA SRS—97.7% and for EBT-XD film—98.97% were obtained. It is concluded that both myQA SRS detectors and EBT-XD films are suitable for SBRT pre-treatment verification, ensuring accuracy and reliability. However, myQA SRS detectors are preferred over EBT-XD film due to the fact that they offer real-time measurements and user-friendly features.

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评估用于立体定向体放射治疗的立体定向高分辨率探测器:myQA® SRS 和 Gafchromic EBT-XD 胶片的比较分析
这项研究旨在评估用于立体定向体放射治疗(SBRT)的剂量测定系统,特别是二维阵列剂量测定系统和胶片剂量测定系统,以探索它们的特点和临床适用性。为此,我们采用了高分辨率的 myQA SRS 探测器和 Gafchromic EBT-XD 胶片。胶片分析包括取决于能量、剂量率、扫描仪方向、扫描侧和曝光后生长的净光学密度 (OD) 值。对于 myQA SRS,信号值根据剂量率(400-1400 MU/min)和角度依赖性(0-180°,间隔 30°)以及 0°、45° 和 90°床角进行评估。治疗前验证包括 32 名 SBRT 患者,将 myQA SRS 结果与使用 Gafchromic EBT-XD 胶片获得的结果进行比较。分析显示,能量和剂量率相关的净外径偏差不到 1%。扫描仪方向导致了 2.5% 的净 OD 变化,而胶片正面和背面扫描方向之间的差异极小(差异为 1.0%)。暴露后六小时内,OD 迅速上升,随后逐渐增加。myQA SRS 检测器的剂量率依赖性为-3.7%(400 MU/min),而 90° 角的角度依赖性为-26.7%。校正因子有效地将这些差异缩小到了 1%。myQA SRS 的伽马通过率为-93.6%(2%/1 毫米),而 EBT-XD 胶片的伽马通过率为-92.8%。3%/1 mm 的伽马通过率有所提高:myQA SRS 为 97.9%,EBT-XD 胶片为 98.16%。相比之下,在 2%/2 mm 和 10% 临界值条件下,myQA SRS 为 97.7%,EBT-XD 胶片为 98.97%。结论是,myQA SRS 检测器和 EBT-XD 胶片都适用于 SBRT 预处理验证,可确保准确性和可靠性。然而,与 EBT-XD 薄膜相比,myQA SRS 检测器具有实时测量和用户友好的特点,因此更受青睐。
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来源期刊
CiteScore
4.00
自引率
5.90%
发文量
53
审稿时长
>36 weeks
期刊介绍: This journal is devoted to fundamental and applied issues in radiation research and biophysics. The topics may include: Biophysics of ionizing radiation: radiation physics and chemistry, radiation dosimetry, radiobiology, radioecology, biophysical foundations of medical applications of radiation, and radiation protection. Biological effects of radiation: experimental or theoretical work on molecular or cellular effects; relevance of biological effects for risk assessment; biological effects of medical applications of radiation; relevance of radiation for biosphere and in space; modelling of ecosystems; modelling of transport processes of substances in biotic systems. Risk assessment: epidemiological studies of cancer and non-cancer effects; quantification of risk including exposures to radiation and confounding factors Contributions to these topics may include theoretical-mathematical and experimental material, as well as description of new techniques relevant for the study of these issues. They can range from complex radiobiological phenomena to issues in health physics and environmental protection.
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