Monkeypox: A re-emerging disease

IF 1.4 4区 医学 Q4 PHARMACOLOGY & PHARMACY Indian Journal of Pharmacology Pub Date : 2024-04-30 DOI:10.4103/ijp.ijp_156_23
Narinderpal Kaur, Jatin Dabar, Pallavi Bassi
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Abstract

The virus known as monkeypox is the source of the zoonotic disease monkeypox, which was historically widespread in Central Africa and West Africa. The cases of monkeypox in humans are uncommon outside of West and Central Africa, but copious nonendemic nations outside of Africa have recently confirmed cases. People when interact with diseased animals, then, they may inadvertently contact monkeypox. There are two drugs in the market: brincidofovir and tecovirimat and both of these drugs are permitted for the cure of monkeypox by the US Food and Drug Administration. The present review summarizes the various parameters of monkeypox in context with transmission, signs and symptoms, histopathological and etiological changes, and possible treatment. Monkeypox is clinically similar to that of smallpox infection but epidemiologically, these two are different, the present study also signifies the main differences and similarities of monkeypox to that of other infectious diseases. As it is an emerging disease, it is important to know about the various factors related to monkeypox so as to control it on a very early stage of transmission.

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猴痘一种重新出现的疾病
猴痘病毒是人畜共患疾病猴痘的病源,猴痘在历史上曾广泛流行于中非和西非。在西非和中非以外地区,人类感染猴痘的病例并不常见,但非洲以外的许多非流行国家最近都出现了确诊病例。人们在与患病动物接触时,可能会无意中感染猴痘。目前市场上有两种药物:布林昔多韦(brincidofovir)和替考韦瑞(tecovirimat),这两种药物都被美国食品和药物管理局批准用于治疗猴痘。本综述总结了猴痘的各种参数,包括传播途径、症状和体征、组织病理学和病原学变化以及可能的治疗方法。猴痘在临床上与天花感染相似,但在流行病学上两者却不同,本研究还指出了猴痘与其他传染病的主要异同。猴痘是一种新出现的疾病,因此了解与猴痘有关的各种因素,以便在猴痘传播的早期阶段对其进行控制是非常重要的。
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来源期刊
CiteScore
4.00
自引率
4.20%
发文量
53
审稿时长
4-8 weeks
期刊介绍: Indian Journal of Pharmacology accepts, in English, review articles, articles for educational forum, original research articles (full length and short communications), letter to editor, case reports and interesting fillers. Articles concerning all aspects of pharmacology will be considered. Articles of general interest (e.g. methods, therapeutics, medical education, interesting websites, new drug information and commentary on a recent topic) are also welcome.
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