Definition and Management of Arrhythmia-induced Cardiomyopathy: Findings from the European Heart Rhythm Association Survey

Teodor Serban, Patrick Badertscher, Jeanne du Fay de Lavallaz, Rui Providencia, Federico Migliore, Giacomo Mugnai, Diego Penela, Laura Perrotta, Michael Kühne, Christian Sticherling, Kyoung-Ryul Julian Chun
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Abstract

Background Arrhythmia-induced Cardiomyopathy (AiCM) represents a subtype of acute heart failure (HF) in the context of sustained arrhythmia. Clear definitions and management recommendations for AiCM are lacking. Purpose The European Heart Rhythm Association Scientific Initiatives Committee (EHRA SIC) conducted a survey to explore the current definitions and management of patients with AiCM among European and non-European electrophysiologists. Methods A 25-item online questionnaire was developed and distributed among EP specialists on the EHRA SIC website and on social media between September 4th and October 5th 2023. Results Of the 206 respondents, 16% were female and 61% were between 30-49 years old. Most of the respondents were EP-Specialists (81%) working at University Hospitals (47%). While most participants (67%) agreed that AiCM should be defined as a left ventricular ejection fraction (LVEF) impairment after new onset of an arrhythmia, only 35% identified a specific LVEF drop to diagnose AiCM with a wide range of values (5-20% LVEF drop). Most respondents considered all available therapies: catheter ablation(93%), electrical cardioversion(83%), antiarrhythmic drugs (76%) and adjuvant HF treatment(76%). 83% of respondents indicated that adjuvant HF treatment should be started at first HF diagnosis prior to antiarrhythmic treatment and 84% agreed it should be stopped within six months after LVEF normalization. Responses for the optimal time point for the first LVEF reassessment during follow-up varied markedly (1 day-6 months after antiarrhythmic treatment). Conclusion This EHRA Survey reveals varying practices regarding AiCM among physicians, highlighting a lack of consensus and heterogenous care of these patients.
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心律失常诱发心肌病的定义和管理:欧洲心脏节律协会的调查结果
背景心律失常诱发的心肌病(AiCM)是持续心律失常情况下急性心力衰竭(HF)的一种亚型。目前尚缺乏针对 AiCM 的明确定义和管理建议。目的 欧洲心脏节律协会科学倡议委员会 (EHRA SIC) 开展了一项调查,以了解欧洲和非欧洲电生理学家目前对 AiCM 患者的定义和管理。方法 2023 年 9 月 4 日至 10 月 5 日期间,在 EHRA SIC 网站和社交媒体上向 EP 专家发放了一份包含 25 个项目的在线问卷。结果 在 206 名受访者中,16% 为女性,61% 年龄在 30-49 岁之间。大多数受访者是在大学医院工作的急诊科专家(81%)(47%)。虽然大多数受访者(67%)同意 AiCM 应定义为新发心律失常后左心室射血分数 (LVEF) 受损,但只有 35% 的受访者确定了诊断 AiCM 的特定 LVEF 下降值(LVEF 下降 5%-20%),且范围很广。大多数受访者考虑了所有可用的治疗方法:导管消融(93%)、心脏电复律(83%)、抗心律失常药物(76%)和高频辅助治疗(76%)。83% 的受访者表示,应在抗心律失常治疗前首次确诊心房颤动时开始辅助治疗,84% 的受访者同意应在 LVEF 恢复正常后六个月内停止辅助治疗。对于随访期间首次 LVEF 重新评估的最佳时间点的答复差异明显(抗心律失常治疗后 1 天-6 个月)。结论 本次 EHRA 调查揭示了医生们对 AiCM 的不同做法,凸显了对这些患者的护理缺乏共识且存在差异。
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